ArticleCough (London, England)2013
Molecular signaling and targets from itch: lessons for cough.
Article in Cough (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Skin hypersensitivity in chronic cough patients: symptom profiles and psychosomatic correlates.Annals of medicine · 2026Article
- Chronic cough and chronic pruritus in older adults: a population-based cross-sectional study.ERJ open research · 2025Article
- Review
- PAR2 Participates in the Development of Cough Hypersensitivity in Guinea Pigs by Regulating TRPA1 Through PKC.Biomolecules · 2025Article
- Peripheral antitussives affect temporal features of tracheobronchial coughing in cats.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- A descending pathway emanating from the periaqueductal gray mediates the development of cough-like hypersensitivity.iScience · 2022Article
- Itch and Cough - Similar Role of Sensory Nerves in Their Pathogenesis.Physiological research · 2020Review
- Peripheral and Central Mechanisms of Itch.Neuron · 2018Review
- Early intervention by Captopril does not improve wound healing of partial thickness burn wounds in a rat model.Burns : journal of the International Society for Burn Injuries · 2018Article
- Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?Pharmaceuticals (Basel, Switzerland) · 2016Review
- Are itch and scratching the nausea and vomiting of skin?Experimental dermatology · 2016Article
- Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms?Pulmonary pharmacology & therapeutics · 2015Review
- Article
- Suppression of the cough reflex by α 2-adrenergic receptor agonists in the rabbit.Physiological reports · 2013Article
- Clinical Aspects of Chronic Idiopathic Postnasal Drip: An Entity Not to Be Overlooked.In vivo (Athens, Greece)Article
- Evaluation methods and influencing factors of cough sensitivity.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Itch is described as an unpleasant sensation that elicits the desire to scratch, which results in the removal of the irritant from the skin. The cough reflex also results from irritation, with the purpose of removing said irritant from the airway. Could cough then be similar to itch? Anatomically, both pathways are mediated by small-diameter sensory fibers. These cough and itch sensory fibers release neuropeptides upon activation, which leads to inflammation of the nerves. Both cough and itch also involve mast cells and their mediators, which are released upon degranulation. This common inflammation and interaction with mast cells are involved in the development of chronic conditions of itch and cough. In this review, we examine the anatomy and molecular mechanisms of itch and compare them to known mechanisms for cough. Highlighting the common aspects of itch and cough could lead to new thoughts and perspectives in both fields.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.