SynthesisBMC medical research methodology2013
"Best fit" framework synthesis: refining the method.
Synthesis in BMC medical research methodology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 257 papers, 59 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
257 citing papers in PubMed, 59 syntheses or guidelines pooled it.
- Barriers to and facilitators of the implementation of Community Health Worker programmes in high-income countries: a systematic review.BMC health services research · 2026Pooled it
- Pooled it
- Exploring strategies and approaches to improve end-of-life care services for people experiencing homelessness: a systematic review and meta-synthesis of qualitative studies.BMC palliative care · 2026Pooled it
- Cultural competency and inclusion training for healthcare professionals: a systematic review to inform training for health research professionals.BMC health services research · 2026Pooled it
- Key Factors for Quality End-of-Life Care for People With Intellectual Disabilities. A Critical Interpretive Synthesis Review Using a 'Best-Fit' Framework Approach.Journal of applied research in intellectual disabilities : JARID · 2026Pooled it
- Developing a novel typology of unprofessional behaviours between healthcare staff: a best fit framework synthesis.BMC health services research · 2026Pooled it
- Medical specialists in LMICs: a systematic review and best-fit framework synthesis of the evidence on their roles and contribution to health systems.BMJ global health · 2026Pooled it
- Diagnostic performance of artificial intelligence in oral squamous cell carcinoma detection: a higher-order evidence synthesis through umbrella review and meta-meta-analysis.Frontiers in dental medicine · 2026Pooled it
- Patients' experiences and perceived outcomes of manual therapy: a qualitative systematic review with framework synthesis.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- Mapping ecological paradigms in educational psychology: a decade of scholarship inFrontiers in psychology · 2026Pooled it
- Understanding access to sexual and reproductive health in general practice using an adapted Candidacy Framework: a systematic review and qualitative evidence synthesis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Pooled it
- Facilitators and Barriers to Effective Implementation of Interprofessional Care for Type 2 Diabetes in the Elderly Population of the Southern Africa Development Community: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Mapping Evidence and Constructing an Analytic Framework: An Umbrella Review Summarizing Primary Care Family Physicians' Experiences With Clinical Integration.Annals of family medicine · 2025Pooled it
- Community views on mass drug administration for soil-transmitted helminths: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Pooled it
- Best fit framework synthesis of qualitative studies on factors associated with medication nonadherence in people with type 2 diabetes using the COM-B model.British journal of clinical pharmacology · 2025Pooled it
- Pooled it
- Experiences of parents of children with mental illnesses: A systematic review and meta-ethnographic synthesis.Family process · 2025Pooled it
- Barriers and Facilitators of User Engagement With Digital Mental Health Interventions for People With Psychosis or Bipolar Disorder: Systematic Review and Best-Fit Framework Synthesis.JMIR mental health · 2025Pooled it
- Factors influencing the utilization of Traditional Chinese Medicine in cancer treatment: a qualitative meta-synthesis of patient and healthcare professional perspectives.Frontiers in medicine · 2025Pooled it
- Factors that influence recruitment to COVID-19 vaccine trials: a qualitative evidence synthesis.Trials · 2024Pooled it
197 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFollowing publication of the first worked example of the "best fit" method of evidence synthesis for the systematic review of qualitative evidence in this journal, the originators of the method identified a need to specify more fully some aspects of this particular derivative of framework synthesis. METHODS AND
resultsWe therefore present a second such worked example in which all techniques are defined and explained, and their appropriateness is assessed. Specified features of the method include the development of new techniques to identify theories in a systematic manner; the creation of an a priori framework for the synthesis; and the "testing" of the synthesis. An innovative combination of existing methods of quality assessment, analysis and synthesis is used to complete the process. This second worked example was a qualitative evidence synthesis of employees' views of workplace smoking cessation interventions, in which the "best fit" method was found to be practical and fit for purpose.
conclusionsThe method is suited to producing context-specific conceptual models for describing or explaining the decision-making and health behaviours of patients and other groups. It offers a pragmatic means of conducting rapid qualitative evidence synthesis and generating programme theories relating to intervention effectiveness, which might be of relevance both to researchers and policy-makers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.