Evidence map›Paper›PMID 23497051›Full record

ArticleLipids in health and disease2013

Lipid-lowering effect of maize-based traditional Mexican food on a metabolic syndrome model in rats.

Juan Manuel Muñoz Cano, Andrea Carrillo Aguilar, Juan Córdova Hernández

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02606812 (Effect of Food Consumption on microRNA Related to Metabolic Syndrome. A Randomized Clinical Trial), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02606812 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effect of Food Consumption on microRNA Related to Metabolic Syndrome. A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad Juárez Autónoma de TabascoRan2017 to 2018Enrolled50ConditionsMetabolic Syndrome XArmsTraditional-food
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Juan Manuel Muñoz CanoUniversidad Juárez Autónoma de Tabasco, División Académica de Ciencias de la Salud, Avenida Méndez 2838-A, Villahermosa, Tabasco, CP 86150, México. juan.munoz@ujat.mx
Andrea Carrillo Aguilar
Juan Córdova Hernández
Universidad Juárez Autónoma de Tabasco · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaize-based food is typical in Mexico and other Mesoamerican countries. Used for millennia, they have recently been replaced by modern food that is associated with an increase in the prevalence of non-communicable chronic diseases. This study was carried out in order to evaluate the effects of traditional food on lipid profiles.

methodsMetabolic syndrome was induced in animals given a 30% sucrose solution. The animals were given maize tortillas (n=5) and maize pozol (n=5), traditional Mexican food items. A control group was given a 30% sucrose solution in the laboratory diet (n=5) and a witness group was given plain water and pellets. Triglycerides, cholesterol and glucose in tail blood were recorded each month between weeks 12 to 24. Blood was obtained from the cardiac cavity on week 28 and triglycerides, total cholesterol, LDL, HDL, C-reactive protein, alanine amino transferase, glucose and glycated hemoglobin were recorded.

resultsThe animals provided with supplementary traditional food presented a lower increase in triglycerides up to week 24 (p<0.001). Data recorded on week 28 showed lower values of LDL (p<0.05), a lower percentage of glycated hemoglobin when maize tortillas were provided (p<0.01) and lower values of alanine amino transferase when both food items were provided (p<0.01).

conclusionsProviding traditional Mexican food generated a protective effect against the intake of a 30% sucrose solution over a long period.

Indexed as

DietAlanine TransaminaseAnimalsBlood GlucoseCholesterol, HDLCholesterol, LDLC-Reactive ProteinDisease Models, AnimalFemaleGlycated HemoglobinMetabolic SyndromeMexicoRatsRats, WistarSucroseTriglyceridesAlanine TransaminaseBlood GlucoseCholesterol, HDLCholesterol, LDLC-Reactive ProteinGlycated HemoglobinSucroseTriglycerides

Identifiers

PMID23497051
PMCPMC3608023
OpenAlexW2127271321

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.