Evidence map›Paper›PMID 23496835›Full record

ArticleBMC gastroenterology2013

Medical and surgical treatment of haemorrhoids and anal fissure in Crohn's disease: a critical appraisal.

Stefano D'Ugo, Luana Franceschilli, Federica Cadeddu, Laura Leccesi, Giovanna Del Vecchio Blanco, Emma Calabrese, Giovanni Milito, Nicola Di Lorenzo, Achille L Gaspari, Pierpaolo Sileri

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 68 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Nonfistulizing Perianal Crohn's Disease.Clinics in colon and rectal surgery · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Rubber band ligation of hemorrhoids: A guide for complications.World journal of gastrointestinal surgery · 2016
    Review
  17. Anal Fissure.Clinics in colon and rectal surgery · 2016
    Review
  18. Sphincterotomy for anal fissure in Crohn's disease: is it dangerous?International journal of colorectal disease · 2016
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stefano D'UgoDepartment of Surgery, University Hospital Tor Vergata, Viale Oxford 81, Rome 00133, Italy. dugo.stefano@gmail.com
Luana Franceschilli
Federica Cadeddu
Laura Leccesi
Giovanna Del Vecchio Blanco
Emma Calabrese
Giovanni Milito
Nicola Di Lorenzo
Achille L Gaspari
Pierpaolo Sileri
University of Rome Tor Vergata · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe principle to avoid surgery for haemorrhoids and/or anal fissure in Crohn's disease (CD) patients is still currently valid despite advances in medical and surgical treatments. In this study we report our prospectively recorded data on medical and surgical treatment of haemorrhoids and anal fissures in CD patients over a period of 8 years.

methodsClinical data of patients affected by perianal disease were routinely and prospectively inserted in a database between October 2003 and October 2011 at the Department of Surgery, Tor Vergata University Hospital, Rome. We reviewed and divided in two groups records on CD patients treated either medically or surgically according to the diagnosis of haemorrhoids or anal fissures. Moreover, we compared in each group the outcome in patients with prior diagnosis of CD and in patients diagnosed with CD only after perianal main treatment.

resultsEighty-six CD patients were included in the study; 45 were treated for haemorrhoids and 41 presented with anal fissure. Conservative approach was initially adopted for all patients; in case of medical treatment failure, the presence of stable intestinal disease made them eligible for surgery. Fifteen patients underwent haemorrhoidectomy (open 11; closed 3; stapled 1), and two rubber band ligation. Fourteen patients required surgery for anal fissure (Botox ± fissurectomy 8; LIS 6). In both groups we observed high complication rate, 41.2% for haemorrhoids and 57.1% for anal fissure. Patients who underwent haemorrhoidectomy without certain diagnosis of CD had significantly higher risk of complications.

conclusionsConservative treatment of proctologic diseases in CD patients has been advocated given the high risk of complications and the evidence that spontaneous healing may also occur. From these preliminary results a role of surgery is conceivable in high selected patients, but definitve conclusions can't be made. Further randomized trials are needed to establish the efficacy of the surgical approach, giving therapeutic recommendations and guidelines.

Indexed as

AdolescentAdultCrohn DiseaseDrug TherapyFemaleFissure in AnoFollow-Up StudiesHemorrhoidectomyHemorrhoidsHumansIncidenceMaleMiddle AgedProctoscopyProspective StudiesRetrospective Studies

Identifiers

PMID23496835
PMCPMC3602071
OpenAlexW2131082872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.