ArticleEthnicity & disease2013
Getting to the height of the matter: the relationship between stature and adiposity in pre-pubertal children.
Article in Ethnicity & disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Pediatric obesity prevention: From naïve examination of energy imbalance towards strategies that influence the competition for nutrient resources among tissues.World journal of clinical pediatrics · 2015Review
- Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals.Journal of clinical & translational endocrinology · 2015Article
- The relationships among total body fat, bone mineral content and bone marrow adipose tissue in early-pubertal girls.BoneKEy reports · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectiveHeight has been inversely associated with cardiometabolic disease, with adiposity as the proposed contributor. Childhood represents a time when underlying metabolic pathways converge to determine growth. Although the extent to which influence is relevant, insulin, as a key growth signaling factor, likely provides key insight into mechanisms linking height and adiposity. Insulin concentration displays well-established sex and racial differences, with hyperinsulinemia more common among African Americans (AA) females relative to European Americans (EA). The objective of our study was to evaluate the relationship between height and adiposity in children. In addition, a secondary objective was to evaluate potential moderation by insulin concentration.
designSeventy-two pre-pubertal children aged 4-10 years (mu = 6.6 +/- .2) participated.
main outcome measuresPercent fat was assessed by DXA and fasting insulin by serum assay.
resultsHeight was positively associated with percent fat in the overall sample (P = .04). When evaluated according to age, an association was identified at age seven years (P = .02). When evaluated by sex, a positive relationship was apparent only in AA girls (P = .05). Inclusion of insulin in the model attenuated all significant associations, barring marginal significance in those aged seven years (P = .08).
conclusionsA positive relationship between height and adiposity is apparent, particularly among those in younger years, which is contrary to what has been consistently reported in adults. Interestingly, age seven years was identified as a point of race-associated divergence in body composition. The degree to which growth-related processes in childhood underlie developmental origins of health disparities warrants further study.
Indexed as
Identifiers
23495625PMC3708689W2405767713What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.