Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2014
Multimodal analgesia for arthroscopic rotator cuff repair: a randomized, placebo-controlled, double-blind trial.
Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02992028 (Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- PROSPECT guideline for rotator cuff repair surgery: systematic review and procedure-specific postoperative pain management recommendations.Anaesthesia · 2019Pooled it
- The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to-Bone Healing: A Systematic Review with Subgroup Meta-Analysis.The Iowa orthopaedic journal · 2019Pooled it
- Platelet-rich plasma supplementation in arthroscopic repair of full-thickness rotator cuff tears: a randomized clinical trial.Musculoskeletal surgery · 2016Trial
- Trial
- Sleep disturbance in patients undergoing shoulder surgery: a current concepts review.JSES reviews, reports, and techniques · 2026Review
- Postoperative opioid-free analgesia with acetaminophen and its impact on pain and postoperative nausea and vomiting following arthroscopic rotator cuff repair: a single-center retrospective study.Journal of pharmaceutical health care and sciences · 2025Article
- Article
- Strategies to mitigate complications in arthroscopic rotator cuff repair.Journal of clinical orthopaedics and trauma · 2025Article
- Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption After Arthroscopic Shoulder Surgery: A Prospective, Randomized, Double-blind Clinical Trial.Medeniyet medical journal · 2023Article
- Comparison of Analgesia Treatment Methods After Arthroscopic Rotator Cuff Repair: A Network Meta-analysis of 42 Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2023Review
- A Historical Analysis of Randomized Controlled Trials in the Management of Pain in Rotator Cuff Tears.Journal of clinical medicine · 2021Review
- An integrated educational and multimodal approach to achieving an opioid-free postoperative course after arthroscopic rotator cuff repair.JSES international · 2021Article
- A Historical Analysis of Randomized Controlled Trials in Rotator Cuff Tears.International journal of environmental research and public health · 2020Review
- Perioperative Pain Control in Upper Extremity Surgery: Prescribing Patterns, Recent Developments, and Opioid-Sparing Treatment Strategies.Hand (New York, N.Y.) · 2019Review
- Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model.Journal of pain research · 2018Article
- Acute postoperative pain after arthroscopic rotator cuff surgery: A review of methods of pain assessment.SICOT-J · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study was to investigate whether a multimodal analgesia (MMA) protocol reduces postoperative pain and opioids consumption in patients undergoing arthroscopic rotator cuff repair.
methodsFifty-four patients scheduled for arthroscopic rotator cuff repair were randomly assigned to either the MMA group or the control group. The primary outcome was visual analog scale (VAS) for pain. Secondary outcome measures included the time required for the VAS pain to reduce to that of a blood draw, (PCA) consumption, rescue morphine consumption, night awakening, and opioid-related side effects.
resultsThe MMA group showed significantly less postoperative pain at postoperative 5 h, and 9 a.m. and 5 p.m. at 4th postoperative day (P < 0.001, = 0.040, and 0.013, respectively). MMA also shortened the time for postoperative pain to reduce down to the blood draw pain level from 5 days in the control group to 2 days in the MMA group. MMA also significantly reduced PCA consumption for up to 24 h postoperatively (P = 0.038) and rescue morphine consumption during the first 6 h and between 48 and 60 h postoperatively (P = 0.036 and 0.044, respectively). No significant differences were observed between the MMA and control groups with respect to side effects.
conclusionThe MMA protocol used in this study was found to reduce postoperative pain and opioid consumption during the acute postoperative period after arthroscopic rotator cuff repair without increasing side effects after arthroscopic rotator cuff repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.