Evidence map›Paper›PMID 23494755›Full record

ReviewCurrent diabetes reports2013

Diabetes mellitus and inflammation.

Eric Lontchi-Yimagou, Eugene Sobngwi, Tandi E Matsha, Andre Pascal Kengne

Abstract readHistorical ArticleReview
PubMed Publisher
In one paragraph

Review in Current diabetes reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 423 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
423citing papers in PubMed, 4 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

423 citing papers in PubMed, 4 syntheses or guidelines pooled it, 813 citations in OpenAlex.

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363 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 5 countries.

Eric Lontchi-YimagouLaboratory for Molecular and Metabolic Diseases, Biotechnology Center, University of Yaoundé 1, Yaoundé, Cameroon.
Eugene Sobngwi
Tandi E Matsha
Andre Pascal Kengne
Université de Yaoundé I · CMCape Peninsula University of Technology · ZAUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) is increasingly common worldwide. Related complications account for increased morbidity and mortality, and enormous healthcare spending. Knowledge of the pathophysiological derangements involved in the occurrence of diabetes and related complications is critical for successful prevention and control solutions. Epidemiologic studies have established an association between inflammatory biomarkers and the occurrence of T2DM and complications. Adipose tissue appears to be a major site of production of those inflammatory biomarkers, as a result of the cross-talk between adipose cells, macrophages, and other immune cells that infiltrate the expanding adipose tissue. The triggering mechanisms of the inflammation in T2DM are still ill-understood. Inflammatory response likely contributes to T2DM occurrence by causing insulin resistance, and is in turn intensified in the presence of hyperglycemia to promote long-term complications of diabetes. Targeting inflammatory pathways could possibly be a component of the strategies to prevent and control diabetes and related complications.

Indexed as

Diabetes Mellitus, Type 2History, 19th CenturyHistory, 20th CenturyHumansInflammationInflammation MediatorsObesityOrgan SpecificityInflammation Mediators

Identifiers

PMID23494755
OpenAlexW2021343620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.