Evidence map›Paper›PMID 23494482›Full record

ReviewInternational ophthalmology2014

Biologic agents in experimental autoimmune uveitis.

Gian Paolo Giuliari, Ama Sadaka, David M Hinkle

Abstract readReview
PubMed Publisher
In one paragraph

Review in International ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Interleukins and cytokine biomarkers in uveitis.Indian journal of ophthalmology · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gian Paolo GiuliariCentro de Cirugía Oftalmológica (CECOF), Caracas, Venezuela, gpgiuliari@gmail.com.
Ama Sadaka
David M Hinkle
California Retina Consultants · USGood Samaritan Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental uveitis models were developed in an effort to elucidate the pathogenesis of human uveitis. The therapeutic effects of numerous anti-inflammatory agents including corticosteroids and immunomodulatory agents including biologic response modifiers have been investigated in both experimental and human uveitis. Monoclonal antibodies to tumor necrosis factor alpha and anti-interleukins, among others, demonstrate efficacy and are employed in the treatment of uveitis refractory to conventional immunomodulatory agents.

Indexed as

ImmunotherapyAnimalsAntibodies, MonoclonalAutoimmune DiseasesBiological FactorsDisease Models, AnimalHumansImmunoconjugatesImmunosuppressive AgentsInterleukinsModels, BiologicalMolecular Targeted TherapyTumor Necrosis Factor-alphaUveitisAntibodies, MonoclonalBiological FactorsImmunoconjugatesImmunosuppressive AgentsInterleukinsTumor Necrosis Factor-alpha

Identifiers

PMID23494482
OpenAlexW2102910424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.