ArticleDie Naturwissenschaften2013
Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans.
Article in Die Naturwissenschaften, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04113876 (Circadian Health in Patients Admitted to Intensive Care Units and Hospitalization), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Circadian Health in Patients Admitted to Intensive Care Units and Hospitalization (CHRONOHOSPI)
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between Chronotype, Physical Activity and Sedentary Behaviour: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Circadian system functional status and sleep in blind subjects with and without conscious light perception.Frontiers in physiology · 2026Article
- Sleep variability and time to achieving pregnancy: findings from a pilot cohort study of women desiring pregnancy.Fertility and sterility · 2025Article
- Effects of Nightshift Work on Blood Metabolites in Female Nurses and Paramedic Staff: A Cross-sectional Study.Annals of work exposures and health · 2023Article
- Age and Chronodisruption in Mouse Heart: Effect of the NLRP3 Inflammasome and Melatonin Therapy.International journal of molecular sciences · 2022Article
- Chronodisruption and Ambulatory Circadian Monitoring in Cancer Patients: Beyond the Body Clock.Current oncology reports · 2022Review
- Article
- Different levels of circadian (de)synchrony -- where does it hurt?F1000Research · 2022Review
- Correlated color temperature and light intensity: Complementary features in non-visual light field.PloS one · 2021Article
- Food as a circadian time cue - evidence from human studies.Nature reviews. Endocrinology · 2020Review
- The Role of Clock Genes in Fibrinolysis Regulation: Circadian Disturbance and Its Effect on Fibrinolytic Activity.Frontiers in physiology · 2020Review
- Circadian disruption: What do we actually mean?The European journal of neuroscience · 2020Review
- Article
- Multilevel Interactions of Stress and Circadian System: Implications for Traumatic Stress.Frontiers in psychiatry · 2019Review
- Assessing Chronotypes by Ambulatory Circadian Monitoring.Frontiers in physiology · 2019Article
- Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation.Frontiers in psychiatry · 2019Review
- Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression.British journal of pharmacology · 2018Review
- Rhythmicity of Mood Symptoms in Individuals at Risk for Psychiatric Disorders.Scientific reports · 2018Article
- Night Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank.Diabetes care · 2018Article
- Prospective Assessment of Daily Patterns of Mood-Related Symptoms.Frontiers in psychiatry · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this Concepts & Synthesis paper, we expand the definition of chronodisruption in humans by proposing that it can be operationalized as the split nexus of internal and external times. With this premise, we suggest how chronotype may be used as a temporal marker (chronomarker) of exposure to chronodisruption in studies of cancer, and beyond, offer cancer risk predictions for observational research on the basis of a chronotype-related hypothesis and corollary, and point to first empirical data in humans. In an a priori way, we examine possible outcomes and perspectives for preventive measures following from our rationale and the suggested chronobiology-driven studies and close with overall advances of chronodisruption research.
Indexed as
Identifiers
23494200What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.