Evidence map›Paper›PMID 23494104›Full record

Trial reportLasers in medical science2014

Comparison of the influence of ozone and laser therapies on pain, swelling, and trismus following impacted third-molar surgery.

Hakki Oguz Kazancioglu, Seref Ezirganli, Nihat Demirtas

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02602431 naunknown statusnot on this map

A Unique Application of Low Laser Therapy After Third Molar Surgery: A Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of Sao PauloRan2014 to 2016Enrolled30ConditionsTrismus, Edema, PainArmsExtra-oral laser irradiation, Intra-oral laser irradiation, Extra-oral placebo, Intra-oral Placebo
NCT05922150 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficiency of Low Level Laser Therapy and Ozone on Sequelae After Extraction of Impacted Mandibular Third Molar

TypeinterventionalSponsorUniversity of BaghdadRan2022 to 2022Enrolled60ConditionsComplications of Extraction of Impacted TeethArmslow level laser therapy, ozone gel
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Cost-Effectiveness Analysis of Photobiomodulation After Third Molar Extraction for Pain Control.International journal of environmental research and public health · 2025
    Pooled it
  2. Pooled it
  3. Third molar removal and its impact on quality of life: systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hakki Oguz KazanciogluDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, 34093, Fatih, Istanbul, Turkey, dt_oguz@yahoo.com.
Seref Ezirganli
Nihat Demirtas
Bezmiâlem Vakıf Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to evaluate the efficacy of the ozone and laser application in the management of pain, swelling, and trismus after third-molar surgery. Sixty consecutive patients with asymptomatic impacted mandibular third molars were recruited into the study. Patients were randomized into three treatment groups of 20 patients each: two study groups (group 1 = low-level laser therapy (LLLT), group 2 = ozone therapy) and a control group (no-LLLT or ozone therapy). Twenty teeth extractions were performed in each group. Evaluations of postoperative pain, the number of analgesics tablets taken, trismus, swelling, and quality of life (Oral Health Impact Profile-14 questionnaire) were made. The sample consisted of 28 female and 32 male patients, whose total mean age was 23.5 ± 3.4 (range, 18-25) years. The pain level and the number of analgesics tablets taken were lower in the ozonated and LLLT applied groups than in the control group. This study showed that ozone and low power laser therapies had a positive effect on the patients' quality of life. Trismus in the LLLT group was significantly less than in the ozonated and control groups (p = 0.033). Ozone application showed no superiority in regards of postoperative swelling; however, LLLT group had significantly lower postoperative swelling. This study demonstrates that ozone and laser therapies are useful for the reduction of postoperative pain and they increase quality of life after third-molar surgery. Although the ozone therapy had no effect on postoperative swelling and trismus after surgical removal of impacted lower third molars, LLLT had a positive effect.

Indexed as

Low-Level Light TherapyAdolescentAdultAnalgesicsEdemaFemaleHumansMaleMolar, ThirdOzonePain MeasurementPostoperative PainSurveys and QuestionnairesTooth, ImpactedTrismusAnalgesicsOzone

Identifiers

PMID23494104
OpenAlexW1994757978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.