Evidence map›Paper›PMID 23493769›Full record

ArticleBlood2013

Too much or too little, how much HDAC activity is good for you?

Patrick Matthias

Abstract readComment
PubMed Publisher
In one paragraph

Article in Blood, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Patrick MatthiasFriedrich Miescher Institute For Biomedical Research, Switzerland.
Friedrich Miescher Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Blood, Heideman and colleagues show that the major class I histone deacetylases (HDACs) HDAC1 and HDAC2 can act to suppress tumors in mouse thymocytes.

Indexed as

AnimalsGene DosageGenes, Tumor SuppressorHistone Deacetylase 1Histone Deacetylase 2Proto-Oncogene Proteins c-mycTumor Suppressor Protein p53Hdac1 protein, mouseHdac2 protein, mouseHistone Deacetylase 1Histone Deacetylase 2Myc protein, mouseProto-Oncogene Proteins c-mycTumor Suppressor Protein p53

Identifiers

PMID23493769
OpenAlexW1994746194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.