ArticleGenome biology and evolution2013
The evolutionary path to extraintestinal pathogenic, drug-resistant Escherichia coli is marked by drastic reduction in detectable recombination within the core genome.
Article in Genome biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Antimicrobial multidrug resistance of Escherichia coli from broiler farms in Zhanjiang, China.PloS one · 2025Article
- Comparative genomic analysis of uropathogenicFrontiers in microbiology · 2023Article
- Large-scale analysis of putative plasmids in clinical multidrug-resistantFrontiers in microbiology · 2023Article
- Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups.Communications biology · 2021Article
- Antimicrobial Resistance ofFrontiers in veterinary science · 2021Article
- Can Pathogenic and Nonpathogenic Bacteria Be Distinguished by Sensory Protein Abundance?Applied and environmental microbiology · 2020Article
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- Genetic Competence Drives Genome Diversity in Bacillus subtilis.Genome biology and evolution · 2018Article
- Genomic Epidemiology of Penicillin-Nonsusceptible Pneumococci with Nonvaccine Serotypes Causing Invasive Disease in the United States.Journal of clinical microbiology · 2017Article
- Recombination-Mediated Host Adaptation by Avian Staphylococcus aureus.Genome biology and evolution · 2017Article
- Combined Analysis of Variation in Core, Accessory and Regulatory Genome Regions Provides a Super-Resolution View into the Evolution of Bacterial Populations.PLoS genetics · 2016Article
- Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Antibiotic Resistance, RAPD- PCR Typing of Multiple Drug Resistant Strains of Escherichia Coli From Urinary Tract Infection (UTI).Journal of clinical and diagnostic research : JCDR · 2016Article
- Directional gene flow and ecological separation inMicrobial genomics · 2015Article
- Article
- Recombinant transfer in the basic genome of Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Tackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics.Microorganisms · 2015Review
- Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis.Nature communications · 2015Article
- Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection.Scientific reports · 2015Article
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4 authors.
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Abstract
Escherichia coli is a highly diverse group of pathogens ranging from commensal of the intestinal tract, through to intestinal pathogen, and extraintestinal pathogen. Here, we present data on the population diversity of E. coli, using Bayesian analysis to identify 13 distinct clusters within the population from multilocus sequence typing data, which map onto a whole-genome-derived phylogeny based on 62 genome sequences. Bayesian analysis of recombination within the core genome identified reduction in detectable core genome recombination as one moves from the commensals, through the intestinal pathogens down to the multidrug-resistant extraintestinal pathogenic clone E. coli ST131. Our data show that the emergence of a multidrug-resistant, extraintestinal pathogenic lineage of E. coli is marked by substantial reduction in detectable core genome recombination, resulting in a lineage which is phylogenetically distinct and sexually isolated in terms of core genome recombination.
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