ArticleIranian journal of basic medical sciences2011
Immunolocalization of galectin-3 in mouse testicular tissue.
Article in Iranian journal of basic medical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Galectin-1 and galectin-3 in male reproduction - impact in health and disease.Seminars in immunopathology · 2025Review
- Targeted disruption of galectin 3 in mice delays the first wave of spermatogenesis and increases germ cell apoptosis.Cellular and molecular life sciences : CMLS · 2021Article
- Immunohistochemical assessment of galectin-3 during pre-implantation in mouse endometrium.Iranian journal of reproductive medicine · 2013Article
- Estimation of Serum and Seminal Plasma Levels of Glactin-1 in Non-Obstructive Azoospermia Cases and Their Correlations with the Rate of Sperm Retrieval: A Comparative Prospective Study.Journal of reproduction & infertilityArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesGalectin-3 (Gal-3) is a member of the ß-galactoside-binding lectins which is expressed in a variety of tissues and plays a role in diverse biological events, such as embryogenesis, adhesion, cellular proliferation, and apoptosis. In this study, the presence and distribution of galectin-3 (Gal-3) in the mouse testicular tissue was investigated. MATERIALS AND
methodsEight adult NMRI mice were used in this study. Animals were sacrificed by decapitation under ether anesthesia. The testes were excised, fixed in 10% buffered formalin and embedded in paraffin for immunohistochemical (IHC) studies. H-score, a semi-quantitative method, was used for scaling the immunostaining.
resultsPositive immunoreactivity to Gal-3 was detected in the connective tissues of the interstitium, Leydig cells and presumably peritubular myoid cells. Seminiferous tubules showed immuno-positive reaction in a stage dependent manner. Stages I-III and IX-XII of spermatogenic cycle showed mild immunostaining, while moderate immunostaining was observed at stages IV-VI. Highest immunoreactivity was observed at stages VII-VIII. H-score assessment showed a significant increase in stages of VII-VIII in comparison to other stages (P< 0.05).
conclusionExpression of Gal-3 in interstitial tissue and seminiferous tubules indicated that this protein probably has multifunctional roles in the mouse testicular tissue.
Indexed as
Identifiers
23493472PMC3586836W2189223906What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.