Evidence map›Paper›PMID 23493354›Full record

ArticleIranian journal of basic medical sciences2012

Inhibitory Activity of Eleven Artemisia Species from Iran against Leishmania Major Parasites.

Seyed Ahmad Emami, Shahrzad Zamanai Taghizadeh Rabe, Ali Ahi, Mahmoud Mahmoudi

Abstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Comparison of the cytotoxic effects of different fractions ofResearch in pharmaceutical sciences · 2020
    Article
  4. Isolation of Two Isochlorogenic Acid Isomers from Phenolic Rich Fraction ofIranian journal of pharmaceutical research : IJPR · 2020
    Article
  5. Article
  6. Sesquiterpene fractions ofIranian journal of basic medical sciences · 2019
    Article
  7. Anti-International journal of environmental research and public health · 2019
    Article
  8. Review
  9. Article
  10. Review
  11. Cytotoxic and apoptotic effects of different extracts ofIranian journal of basic medical sciences · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seyed Ahmad EmamiDepartment of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Shahrzad Zamanai Taghizadeh Rabe
Ali Ahi
Mahmoud Mahmoudi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAnnual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. Artemisia genus is a traditional medicinal plant in Iran. The aim of this study was to examine the leishmanicidal activity of various Iranian Artemisia species extracts. MATERIALS AND

methodsDifferent extracts were gathered from eleven Iranian Artemisia species. Their leishmanicidal activities against the growth of Leishmania major (L. major) promastigotes were examined as the half maximal inhibitory concentration (IC50) using MTT assay.

resultsObtained results showed that ethanol extracts especially those taken from A. ciniformis, A. santolina and A. kulbadica have the strongest effects.

conclusionLooking for the effective leishmanicidal agents from natural resources in Iran, we found that the ethanol extract of collected Artemisia species had significant effect on in vitro leishmanicidal activity and may be suitable candidates in the treatment of leishmaniasis.

Indexed as

ArtemisiaLeishmania majorLeishmanicidal activityMTT assayPromastigote

Identifiers

PMID23493354
PMCPMC3586874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.