ArticleFrontiers in integrative neuroscience2013
Axonal and glial microstructural information obtained with diffusion-weighted magnetic resonance spectroscopy at 7T.
Article in Frontiers in integrative neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06940609 (Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation (MANIFEST)
Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Diffusion magnetic resonance spectroscopy captures microglial reactivity related to gut-derived systemic lipopolysaccharide: A preliminary study.Brain, behavior, and immunity · 2024Article
- Multinuclear Magnetic Resonance Spectroscopy at Ultra-High-Field: Assessing Human Cerebral Metabolism in Healthy and Diseased States.Metabolites · 2023Review
- Longitudinal Monitoring of Microstructural Alterations in Cerebral Ischemia with in Vivo Diffusion-weighted MR Spectroscopy.Radiology · 2023Article
- Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington's disease.NeuroImage. Clinical · 2023Observational
- COnstrained Reference frame diffusion TEnsor Correlation Spectroscopic (CORTECS) MRI: A practical framework for high-resolution diffusion tensor distribution imaging.Frontiers in neuroscience · 2022Article
- Article
- Cytosolic diffusivity and microscopic anisotropy of N-acetyl aspartate in human white matter with diffusion-weighted MRS at 7 T.NMR in biomedicine · 2021Article
- Functional and structural impairment of transcallosal motor fibres in ALS: a study using transcranial magnetic stimulation, diffusion tensor imaging, and diffusion weighted spectroscopy.Brain imaging and behavior · 2021Article
- A Magnetic Resonance Spectroscopy Study of Superior Visual Search Abilities in Children with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Article
- Revisiting double diffusion encoding MRS in the mouse brain at 11.7T: Which microstructural features are we sensitive to?NeuroImage · 2020Article
- Glutamate diffusion in the rat brain in vivo under light and deep anesthesia conditions.Magnetic resonance in medicine · 2019Article
- Apparent diffusion coefficients of the five major metabolites measured in the human brain in vivo at 3T.Magnetic resonance in medicine · 2018Article
- Magnetic resonance temporal diffusion tensor spectroscopy of disordered anisotropic tissue.Scientific reports · 2018Article
- Metabolite diffusion up to very high b in the mouse brain in vivo: Revisiting the potential correlation between relaxation and diffusion properties.Magnetic resonance in medicine · 2017Article
- Longitudinal MR spectroscopy of neurodegeneration in multiple sclerosis with diffusion of the intra-axonal constituentNeuroImage. Clinical · 2017Article
- Distinguishing neuronal from astrocytic subcellular microstructures using in vivo Double Diffusion Encoded 1H MRS at 21.1 T.PloS one · 2017Article
- Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites.Brain : a journal of neurology · 2016Article
- Brain intracellular metabolites are freely diffusing along cell fibers in grey and white matter, as measured by diffusion-weighted MR spectroscopy in the human brain at 7 T.Brain structure & function · 2016Article
- Estimation of Bounded and Unbounded Trajectories in Diffusion MRI.Frontiers in neuroscience · 2016Article
- Reproducibility and optimization of in vivo human diffusion-weighted MRS of the corpus callosum at 3 T and 7 T.NMR in biomedicine · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diffusion-weighted magnetic resonance spectroscopy (DWS) offers unique access to compartment-specific microstructural information on tissue, and potentially sensitive detection of compartment-specific changes in disease. The specificity of DWS is, however, offset by its relative low sensitivity, intrinsic to all MRS-based methods, and further exacerbated by the signal loss due to the diffusion weighting and long echo times. In this work we first provide an experimental example for the type of compartment-specific information that can be obtained with DWS from a small volume of interest (VOI) in brain white matter. We then propose and discuss a strategy for the analysis of DWS data, which includes the use of models of diffusion in compartments with simple geometries. We conclude with a broader discussion of the potential role of DWS in the characterization of tissue microstructure and the complementarity of DWS with less-specific but more sensitive microstructural tools such as diffusion tensor imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.