Evidence map›Paper›PMID 23491525›Full record

ArticleDiabetes care2013

Psoriasis and new-onset diabetes: a Danish nationwide cohort study.

Usman Khalid, Peter Riis Hansen, Gunnar Hilmar Gislason, Jesper Lindhardsen, Søren Lund Kristensen, Signe Abitz Winther, Lone Skov, Christian Torp-Pedersen, Ole Ahlehoff

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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  2. Pooled it
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  12. Diabetes Detection and Prevention in Dermatology.Dermatology practical & conceptual · 2021
    Review
  13. Comorbidity in Men with Psoriasis.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Usman KhalidDepartment of Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark. usman.khalid@regionh.dk
Peter Riis Hansen
Gunnar Hilmar Gislason
Jesper Lindhardsen
Søren Lund Kristensen
Signe Abitz Winther
Lone Skov
Christian Torp-Pedersen
Ole Ahlehoff
Gentofte Hospital · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePsoriasis is associated with increased risk of cardiovascular events and increased prevalence of cardiovascular risk factors. Diabetes mellitus (DM) is a major contributor to cardiovascular morbidity and mortality that may be associated with psoriasis, but conflicting results have been presented and nationwide data on the risk of new-onset DM in patients with psoriasis have not been reported. RESEARCH DESIGN AND

methodsThe study comprised a Danish population ≥ 10 years of age on 1 January 1997 who were followed until new-onset DM, death, or 31 December 2009. Information on comorbidity, concomitant medication, and socioeconomic status was linked on an individual level. The primary study end point was DM requiring pharmacotherapy. Incidence rates for the development of DM events per 1,000 observational years were calculated and adjusted. Incidence rate ratios (IRRs) were estimated by Poisson regression.

resultsA total of 4,614,807 subjects were eligible for analysis, with a maximum follow-up of 13 years. In the study period, 52,613 patients with psoriasis, including 6,784 patients with severe psoriasis, were identified. The overall incidence rates for new-onset DM were 3.67 (CI 3.65-3.69), 6.93 (6.63-7.25), and 9.65 (8.68-10.73) for the reference population, mild psoriasis, and severe psoriasis, respectively. Compared with the reference population, the IRR of new-onset DM was increased in all patients with psoriasis, i.e., IRR 1.49 (CI 1.43-1.56) and 2.13 (1.91-2.37) for those with mild and severe psoriasis.

conclusionsIn this nationwide cohort, psoriasis was associated with increased incidence rates of new-onset DM. The association remained statistically significant after adjustment for confounding factors.

Indexed as

AdultChildCohort StudiesComorbidityDenmarkDiabetes MellitusFemaleHumansIncidenceMalePsoriasisRisk Factors

Identifiers

PMID23491525
PMCPMC3714512
OpenAlexW2118509723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.