Evidence map›Paper›PMID 23490282›Full record

ReviewCurrent opinion in cell biology2013

Functions of the centromere and kinetochore in chromosome segregation.

Frederick G Westhorpe, Aaron F Straight

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 131 citations in OpenAlex.

  1. Article
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  5. The enigma of the B chromosome-specific behaviour.Frontiers in plant science · 2026
    Review
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  20. CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Frederick G WesthorpeDepartment of Biochemistry, Stanford University Medical School, Stanford, CA 94305, United States.
Aaron F Straight
Stanford University · US

Funding

Mechanisms of Kinetochore AssemblyR01GM074728 · NIGMS · STANFORD UNIVERSITY · PI Aaron F Straight · 2005 to 2026
$6.6M
NIGMS NIH HHS R01 GM074728
6 · The paper itself

Abstract

Centromeres play essential roles in equal chromosome segregation by directing the assembly of the microtubule binding kinetochore and serving as the cohesion site between sister chromatids. Here, we review the significant recent progress in our understanding of centromere protein assembly and how centromere proteins form the foundation of the kinetochore.

Indexed as

Chromosome SegregationAnimalsCentromereChromatidsDNA-Binding ProteinsHumansKinetochoresMicrotubulesProtein BindingDNA-Binding Proteins

Identifiers

PMID23490282
PMCPMC3687001
OpenAlexW2085407032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.