Evidence map›Paper›PMID 23490213›Full record

ReviewTrends in biotechnology2013

Exterior design: strategies for redecorating the bacterial surface with small molecules.

Samir Gautam, Thomas J Gniadek, Taehan Kim, David A Spiegel

Abstract readReview
In one paragraph

Review in Trends in biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Bacteria-Based Living Probes: Preparation and the Applications in Bioimaging and Diagnosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Imaging Bacterial Cell Wall Biosynthesis.Annual review of biochemistry · 2018
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samir GautamDepartment of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Thomas J Gniadek
Taehan Kim
David A Spiegel

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Small-Molecule Antibody Recruiting Therapeutics for Treating Human DiseaseDP2OD002913 · OD · YALE UNIVERSITY · PI SPIEGEL, DAVID A · 2007 to 2009
$2.6M
Small Molecule Antibody Mimics: Toward a New Paradigm in Targeted Cancer TherapyR01GM100283 · NIGMS · YALE UNIVERSITY · PI SPIEGEL, DAVID A · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM100283NIGMS NIH HHS R01 GM100283-01A1NIGMS NIH HHS T32 GM007205NIGMS NIH HHS T32GM07205NIH HHS 1DP2OD002913-01NIH HHS DP2 OD002913
6 · The paper itself

Abstract

Recombinant techniques for expressing heterologous proteins and sugars on the surface of bacteria have been known since the 1980s, and have proven useful in a variety of settings from biocatalysis to vaccinology. The past decade has also seen the emergence of novel methods that allow modification of bacterial surfaces with small non-biological compounds. Such technologies enable researchers to harness the unique properties of synthetic materials on a live bacterial platform, opening the door to an exciting new set of applications. Here we review strategies for bacterial surface display and describe how they have been applied thus far. We believe that chemical surface display holds great potential for advancing research in basic bacteriology and applied fields of biotechnology and biomedicine.

Indexed as

BacteriaBiotechnologyRecombinant ProteinsSurface PropertiesSynthetic BiologyRecombinant Proteins

Identifiers

PMID23490213
PMCPMC3641905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.