Evidence map›Paper›PMID 23489335›Full record

ReviewImmunology2013

Tissue-specific effector functions of innate lymphoid cells.

Niklas K Björkström, Eliisa Kekäläinen, Jenny Mjösberg

Open access · greenAbstract readReview
In one paragraph

Review in Immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Immunobiology of the biliary tract system.Journal of hepatology · 2022
    Review
  8. Review
  9. Article
  10. CD8Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. MICA SNPs and the NKG2D system in virus-induced HCC.Journal of gastroenterology · 2015
    Review
  18. Group 2 innate lymphoid cells in health and disease.Cold Spring Harbor perspectives in biology · 2015
    Review
  19. Review
  20. Immune cells and metabolic dysfunction.Seminars in immunopathology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Niklas K BjörkströmCentre for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Eliisa Kekäläinen
Jenny Mjösberg
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) is the collective term for a group of related innate lymphocytes, including natural killer (NK) cells and the more recently discovered non-NK ILCs, which all lack rearranged antigen receptors such as those expressed by T and B cells. Similar to NK cells, the newly discovered ILCs depend on the transcription factor Id2 and the common γ-chain of the interleukin-2 receptor for development. However, in contrast to NK cells, non-NK ILCs also require interleukin-7. In addition to the cytotoxic functions of NK cells, assuring protection against tumour development and viruses, new data indicate that ILCs contribute to a wide range of homeostatic and pathophysiological conditions in various organs via specialized cytokine production capabilities. Here we summarize current knowledge on ILCs with a particular emphasis on their tissue-specific effector functions, in the gut, liver, lungs and uterus. When possible, we try to highlight the role that these cells play in humans.

Indexed as

Immunity, InnateAnimalsCytokinesFemaleGastrointestinal TractHumansImmunity, MucosalKiller Cells, NaturalLiverLungLymphocyte SubsetsMalePhenotypeReceptors, CytokineSignal TransductionUterusCytokinesReceptors, Cytokineeffector functionsinnate lymphoid cellsnatural killer cellstissue immunology

Identifiers

PMID23489335
PMCPMC3719059
OpenAlexW2021056052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.