ArticleProceedings. Biological sciences2013
Trabecular bone microstructure scales allometrically in the primate humerus and femur.
Article in Proceedings. Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 113 citations in OpenAlex.
- The impact of footwear on human talar trabecular architecture.Journal of anatomy · 2026Article
- Variation in trabecular bone microarchitecture across rhesus macaque (Macaca mulatta) load-bearing joints.Journal of anatomy · 2026Article
- How do forelimb long bones adapt in rhinoceroses? An in-depth examination of their microanatomy.Journal of anatomy · 2026Article
- Whole-Epiphysis Trabecular Bone in Tamarin Limbs Suggests Effects of Leaping Distance Alongside Non-Biomechanical Factors.American journal of biological anthropology · 2026Article
- A 50-year perspective on the use and potential of artiodactyl calcanei in bone adaptation studies.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Microanatomy of Dermal Roofing Bones in the Skull of Pipoid Frogs.Journal of morphology · 2025Article
- Locomotor signals in the trabecular structure of the hominoid clavicle.Journal of anatomy · 2025Article
- The helmeted hornbill casque is reinforced by a bundle of exceptionally thick, rod-like trabeculae.Annals of the New York Academy of Sciences · 2025Article
- Trabecular architecture of the distal femur in extant hominids.Journal of anatomy · 2024Article
- Small skeletons show size-specific scaling: an exploration of allometry in the mammalian lumbar spine.Proceedings. Biological sciences · 2024Article
- From Fairies to Giants: Untangling the Effect of Body Size, Phylogeny, and Ecology on Vertebral Bone Microstructure of Xenarthran Mammals.Integrative organismal biology (Oxford, England) · 2023Article
- Size And Locomotor Ecology Have Differing Effects on the External and Internal Morphologies of Squirrel (Rodentia: Sciuridae) Limb Bones.Integrative organismal biology (Oxford, England) · 2023Article
- Trabecular bone ontogeny tracks neural development and life history among humans and non-human primates.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Growth and development of trabecular structure in the calcaneus of Japanese macaques (Macaca fuscata) reflects locomotor behavior, life history, and neuromuscular development.Journal of anatomy · 2022Article
- Vertebral Trabecular Bone Mechanical Properties Vary Among Functional Groups of Cetaceans.Integrative organismal biology (Oxford, England) · 2022Article
- Cortical and trabecular bone structure of the hominoid capitate.Journal of anatomy · 2021Article
- Microarchitecture of cetacean vertebral trabecular bone among swimming modes and diving behaviors.Journal of anatomy · 2021Article
- Dietary Soybean Oil Supplementation Affects Keel Bone Characters and Daily Feed Intake but Not Egg Production and Quality in Laying Hens Housed in Furnished Cages.Frontiers in veterinary science · 2021Article
- Study of Sexual Dimorphism in Metatarsal Bones: Geometric and Inertial Analysis of the Three-Dimensional Reconstructed Models.Frontiers in endocrinology · 2021Article
- Bone Phenotyping Approaches in Human, Mice and Zebrafish - Expert Overview of the EU Cost Action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork").Frontiers in endocrinology · 2021Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most analyses of trabecular microarchitecture in mammals have focused on the functional significance of interspecific variation, but they have not effectively considered the influence of body size or phylogeny on bone architecture. The goals of this study were to determine the relationship between trabecular bone and body size in the humeral and femoral heads of extant primates, and to assess the influence of phylogeny on bone microstructure. Using a sample of 235 individuals from 34 primate species, ranging in body size from 0.06 to 130 kg, the relationships between trabecular bone structure and body size were assessed by using conventional and phylogenetic regression analyses. Bone volume fraction, trabecular thickness and trabecular spacing increase with body size, whereas bone surface-area-to-volume ratio decreases. Shape variables such as trabecular number, connectivity density and degree of anisotropy scale inversely with size. Most of these variables scale with significant negative allometry, except bone surface-area-to-volume ratio, which scales with slight positive allometry. Phylogenetic regressions indicate a relatively weak phylogenetic signal in some trabecular bone variables. These data demonstrate that, relative to body size, large primates have thinner and more tightly packed trabeculae than small primates. The relatively thin trabeculae in large primates and other mammals, coupled with constraints on trabecular thickness related to osteocyte function, suggest that increased skeletal loads in the postcranial joints of large mammals are probably mitigated not only through alterations in trabecular microarchitecture, but also through other mechanisms such as changes in cortical bone distribution, limb posture and gait speed.
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