Evidence map›Paper›PMID 23484140›Full record

ArticleBioMed research international2013

Antioxidant and hepatoprotective effect of aqueous extract of germinated and fermented mung bean on ethanol-mediated liver damage.

Norlaily Mohd Ali, Hamidah Mohd Yusof, Kamariah Long, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Mohd Puad Abdullah, Noorjahan Banu Alitheen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Biosynthesis of Gamma-Aminobutyric Acid (GABA) byCurrent issues in molecular biology · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Ameliorative and Antioxidative Potential ofAntioxidants (Basel, Switzerland) · 2022
    Article
  10. Anti-Inflammatory and Anti-Colon Cancer Activities of Mung Bean Grown in Burkina Faso.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Nutrients · 2020
    Article
  16. Mung Bean (Nutrients · 2019
    Review
  17. Article
  18. Fermented Citrus Lemon Reduces Liver Injury Induced by Carbon Tetrachloride in Rats.Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Norlaily Mohd AliDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Hamidah Mohd Yusof
Kamariah Long
Swee Keong Yeap
Wan Yong Ho
Boon Kee Beh
Soo Peng Koh
Mohd Puad Abdullah
Noorjahan Banu Alitheen
Universiti Putra Malaysia · MYMalaysian Agricultural Research and Development Institute · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mung bean is a hepatoprotective agent in dietary supplements. Fermentation and germination processes are well recognized to enhance the nutritional values especially the concentration of active compounds such as amino acids and GABA of various foods. In this study, antioxidant and hepatoprotective effects of freeze-dried mung bean and amino-acid- and GABA-enriched germinated and fermented mung bean aqueous extracts were compared. Liver superoxide dismutase (SOD), malondialdehyde (MDA), ferric reducing antioxidant power (FRAP), nitric oxide (NO) levels, and serum biochemical profile such as aspartate transaminase (AST), alanine transaminase (ALT), triglycerides (TG), and cholesterol and histopathological changes were examined for the antioxidant and hepatoprotective effects of these treatments. Germinated and fermented mung bean have recorded an increase of 27.9 and 7.3 times of GABA and 8.7 and 13.2 times of amino acid improvement, respectively, as compared to normal mung bean. Besides, improvement of antioxidant levels, serum markers, and NO level associated with better histopathological evaluation indicated that these extracts could promote effective recovery from hepatocyte damage. These results suggested that freeze-dried, germinated, and fermented mung bean aqueous extracts enriched with amino acids and GABA possessed better hepatoprotective effect as compared to normal mung bean.

Indexed as

GerminationAnimalsAntioxidantsCentral Nervous System DepressantsChemical and Drug Induced Liver InjuryEthanolFabaceaeGABA Agentsgamma-Aminobutyric AcidMaleMalondialdehydeMiceMice, Inbred BALB CNitric OxidePlant ExtractsSuperoxide DismutaseAntioxidantsCentral Nervous System DepressantsEthanolGABA Agentsgamma-Aminobutyric AcidMalondialdehydeNitric OxidePlant ExtractsSuperoxide Dismutase

Identifiers

PMID23484140
PMCPMC3591205
OpenAlexW1985082870

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.