Evidence map›Paper›PMID 23484112›Full record

ArticleBioMed research international2013

Functionalized magnetic nanoparticles for the detection and quantitative analysis of cell surface antigen.

Daryoush Shahbazi-Gahrouei, Mohammad Abdolahi, Sayyed Hamid Zarkesh-Esfahani, Sophie Laurent, Corine Sermeus, Cordula Gruettner

Abstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Magnetic Iron Oxide Nanoparticles as TAvicenna journal of medical biotechnology
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daryoush Shahbazi-GahroueiDepartment of Medical Physics and Medical Engineering, School of Medicine, Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran. shahbazi@med.mui.ac.ir
Mohammad Abdolahi
Sayyed Hamid Zarkesh-Esfahani
Sophie Laurent
Corine Sermeus
Cordula Gruettner

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell surface antigens as biomarkers offer tremendous potential for early diagnosis, prognosis, and therapeutic response in a variety of diseases such as cancers. In this research, a simple, rapid, accurate, inexpensive, and easily available in vitro assay based on magnetic nanoparticles and magnetic cell separation principle was applied to identify and quantitatively analyze the cell surface antigen expression in the case of prostate cancer cells. Comparing the capability of the assay with flow cytometry as a gold standard method showed similar results. The results showed that the antigen-specific magnetic cell separation with antibody-coated magnetic nanoparticles has high potential for quantitative cell surface antigen detection and analysis.

Indexed as

Antibodies, NeoplasmAntigens, NeoplasmCell Line, TumorCell SeparationHumansMagnetite NanoparticlesMaleProstatic NeoplasmsAntibodies, NeoplasmAntigens, NeoplasmMagnetite Nanoparticles

Identifiers

PMID23484112
PMCPMC3591120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.