ArticlePloS one2013
Factors associated with lung function decline in patients with non-tuberculous mycobacterial pulmonary disease.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Risk of incident chronic obstructive pulmonary disease during longitudinal follow-up in patients with nontuberculous mycobacterial pulmonary disease.Respiratory research · 2024Article
- Phenotypical characteristics of nontuberculous mycobacterial infection in patients with bronchiectasis.Respiratory research · 2024Observational
- Proposed Etiotypes for Chronic Obstructive Pulmonary Disease: Controversial Issues.Tuberculosis and respiratory diseases · 2024Article
- The cell envelope of Mycobacterium abscessus and its role in pathogenesis.PLoS pathogens · 2023Review
- Identification of Significant Pathogenic Nontuberculous Mycobacteria Species from Presumptive TB Patients Using PartialInfection and drug resistance · 2023Article
- The Impact of Nontuberculous Mycobacteria Species on Mortality in Patients With Nontuberculous Mycobacterial Lung Disease.Frontiers in microbiology · 2022Article
- The Clinical Significance of Programmed Death-1, Regulatory T Cells and Myeloid Derived Suppressor Cells in Patients with Nontuberculous Mycobacteria-Lung Disease.Journal of clinical medicine · 2019Article
- Treatment ofTuberculosis and respiratory diseases · 2019Review
- Surgical management of non-cystic fibrosis bronchiectasis.Journal of thoracic disease · 2018Review
- The Clarithromycin Susceptibility Genotype Affects the Treatment Outcome of Patients with Mycobacterium abscessus Lung Disease.Antimicrobial agents and chemotherapy · 2018Article
- Performance of a Highly Sensitive Mycobacterium tuberculosis Complex Real-Time PCR Assay for Diagnosis of Pulmonary Tuberculosis in a Low-Prevalence Setting: a Prospective Intervention Study.Journal of clinical microbiology · 2018Article
- Change in lung function in never-smokers with nontuberculous mycobacterial lung disease: A retrospective study.Journal of clinical tuberculosis and other mycobacterial diseases · 2018Article
- Plasma Biomarkers Can Predict Treatment Response in Tuberculosis Patients: A Prospective Observational Study.Medicine · 2015Observational
- Mycobacterium abscessus Complex Infections in Humans.Emerging infectious diseases · 2015Article
- Clinical findings in relation to mortality in non-tuberculous mycobacterial infections: patients with Mycobacterium avium complex have better survival than patients with other mycobacteria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Article
- Factors associated with quality of life measured by EQ-5D in patients with nontuberculous mycobacterial pulmonary disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- Article
- Nontuberculous mycobacterial infection is associated with increased respiratory failure: a nationwide cohort study.PloS one · 2014Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is paucity of risk factors on lung function decline among patients with non-tuberculous mycobacteria (NTM) pulmonary disease in literature.
methodsPatients with NTM pulmonary disease between January 2000 and April 2011 were retrospectively selected. Sixty-eight patients had at least two pulmonary function tests within a mean follow-up period of 47 months.
resultsSixty-eight patients were included. They had a median age of 65 years and 65% had impaired lung function (Forced expiratory volume in 1 second [FEV1] <80% of predicted value). The mean FEV1 decline was 48 ml/year. By linear regression, younger age (beta: 0.472, p<0.001), initial FEV1>50% of predicted value (beta: 0.349, p = 0.002), male sex (beta: 0.295, p = 0.018), bronchiectasis pattern (beta: 0.232, p = 0.035), and radiographic score >3 (beta: 0.217, p = 0.049) were associated with greater FEV1 decline. Initial FEV1>50% of predicted value (beta: 0.263, p = 0.032) was also associated with greater FVC annual decline, whereas M. kansasii pulmonary disease was marginally associated with greater annual FVC decline (beta: 0.227, p = 0.062).
conclusionsNTM pulmonary disease is associated with greater decline in lung function in patients who are young, male, with bronchiectasis, and with a high radiographic score. Special attention should be given to patients with these risk factors.
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