Evidence map›Paper›PMID 23483772›Full record

ArticleWorld journal of gastroenterology2013

Gastric adenocarcinoma arising in gastritis cystica profunda presenting with selective loss of KCNE2 expression.

Natsumi Kuwahara, Riko Kitazawa, Koto Fujiishi, Yusa Nagai, Ryuma Haraguchi, Sohei Kitazawa

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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  8. ATranslational cancer research · 2022
    Article
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  11. Role of ion channels in gastrointestinal cancer.World journal of gastroenterology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Natsumi KuwaharaDepartment of Molecular Pathology, Ehime University, Graduate School of Medicine, Ehime 791-0295, Japan.
Riko Kitazawa
Koto Fujiishi
Yusa Nagai
Ryuma Haraguchi
Sohei Kitazawa
Ehime University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastritis cystica profunda (GCP) is a rare condition caused by ectopic entrapment of gastric glands, probably secondary to the disruption of muscularis mucosae. GCP is often associated with gastric adenocarcinoma, and loss of the KCNE2 subunit from potassium channel complexes is considered a common primary target molecule leads to both GCP and malignancy. In this study, we, for the first time, analyzed the expression of KCNE2 in surgically excised tissue from human gastric cancer associated with GCP and confirmed that reduced KCNE2 expression correlates with disease formation.

Indexed as

AdenocarcinomaBiomarkers, TumorBiopsyDown-RegulationGastrectomyGastric MucosaGastritisHumansImmunohistochemistryMaleMiddle AgedPotassium Channels, Voltage-GatedStomach NeoplasmsBiomarkers, TumorKCNE2 protein, humanPotassium Channels, Voltage-GatedGastritis cystica profundaImmunohistochemistryKCNE2

Identifiers

PMID23483772
PMCPMC3587490
OpenAlexW2053446035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.