ArticleAdvanced functional materials2013
Antibiotic-Releasing Silk Biomaterials for Infection Prevention and Treatment.
Article in Advanced functional materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 188 citations in OpenAlex.
- Polyphosphate-crosslinked hydrogels: structural design and bioactivity for tissue engineering scaffolds.RSC advances · 2026Article
- Investigation of antibiotic release from amoxicillin- and clindamycin-impregnated silk and Vicryl suture materials: an in vitro study.BMC oral health · 2026Article
- Bio-enhanced silk fibroin-based scaffolds for chronic diabetic foot ulcers.Burns & trauma · 2026Review
- Permselectivity of Silk Fibroin Hydrogels for Advanced Drug Delivery Neurotherapies.Biomacromolecules · 2024Article
- The Application of Regenerated Silk Fibroin in Tissue Repair.Materials (Basel, Switzerland) · 2024Review
- Review
- Use of Biomaterials in 3D Printing as a Solution to Microbial Infections in Arthroplasty and Osseous Reconstruction.Biomimetics (Basel, Switzerland) · 2024Review
- Fucoidan- and Ciprofloxacin-Doped Plasma-Activated Polymer Coatings on Biodegradable Zinc: Hemocompatibility and Drug Release.ACS omega · 2023Article
- Silk fibroin-based embolic agent for transhepatic artery embolization with multiple therapeutic potentials.Journal of nanobiotechnology · 2023Article
- Recent developments in natural biopolymer based drug delivery systems.RSC advances · 2023Review
- Instantaneous Formation of Silk Protein Aerosols and Fibers with a Portable Spray Device Under Ambient Conditions.Advanced materials technologies · 2023Article
- Clinical Use of Non-Suture Silk-Containing Products: A Systematic Review.Biomimetics (Basel, Switzerland) · 2023Review
- A comprehensive review of silk-fibroin hydrogels for cell and drug delivery applications in tissue engineering and regenerative medicine.Computational and structural biotechnology journal · 2023Review
- Silk fibroin carriers with sustained release capacity for treating neurological diseases.Frontiers in pharmacology · 2023Review
- Silk Fibroin as an Efficient Biomaterial for Drug Delivery, Gene Therapy, and Wound Healing.International journal of molecular sciences · 2022Review
- Localized, on-demand, sustained drug delivery from biopolymer-based materials.Expert opinion on drug delivery · 2022Article
- Surgical Applications of Materials Engineered with Antimicrobial Properties.Bioengineering (Basel, Switzerland) · 2022Review
- Biocompatible Materials in Otorhinolaryngology and Their Antibacterial Properties.International journal of molecular sciences · 2022Review
- A clinical comparison of pure knitted silk and a complex synthetic skin substitute for the treatment of partial thickness burns.International wound journal · 2022Article
- Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Effective treatment of infections in avascular and necrotic tissues can be challenging due to limited penetration into the target tissue and systemic toxicities. Controlled release polymer implants have the potential to achieve the high local concentrations needed while also minimizing systemic exposure. Silk biomaterials possess unique characteristics for antibiotic delivery including biocompatibility, tunable biodegradation, stabilizing effects, water-based processing and diverse material formats. We report on functional release of antibiotics spanning a range of chemical properties from different material formats of silk (films, microspheres, hydrogels, coatings). The release of penicillin and ampicillin from bulk-loaded silk films, drug-loaded silk microspheres suspended in silk hydrogels and bulk-loaded silk hydrogels was investigated and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.