Evidence map›Paper›PMID 23483379›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2013

Physical activity and health outcomes among HIV-infected men who have sex with men: a longitudinal mediational analysis.

Aaron J Blashill, Kenneth H Mayer, Heidi Crane, Jessica F Magidson, Chris Grasso, W Christopher Mathews, Michael S Saag, Steven A Safren

Abstract readMulticenter Study
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Behavioral and Physical Activity Interventions for HAND.Current topics in behavioral neurosciences · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Towards integrated multiple behavior management for HIV and chronic conditions: a comment on Blashill et al.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2013
    Article
  12. Prevention of stroke in people living with HIV.Progress in cardiovascular diseases
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Aaron J BlashillMassachusetts General Hospital, Boston, MA, USA, ablashill@partners.org.
Kenneth H Mayer
Heidi Crane
Jessica F Magidson
Chris Grasso
W Christopher Mathews
Michael S Saag
Steven A Safren
Massachusetts General Hospital · USBowdoin College · USFenway Health · USHarvard University · USUniversity of Alabama at Birmingham · USUniversity of California San Diego Medical Center · USUniversity of Washington · US

Funding

Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Optimal assessment of HAART adherence in routine clinical careR01MH084759 · NIMH · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M. · 2008 to 2012
$2.9M
The MGH Global Psychiatric Clinical Research Training ProgramT32MH093310 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FRICCHIONE, GREGORY L, HENDERSON, DAVID C · 2012 to 2016
$1.3M
Addressing psychosocial comorbidities in HIV treatment and preventionK24MH094214 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2011 to 2015
$858k
Body Image and Self-care in HIV-infected MSMK23MH096647 · NIMH · SAN DIEGO STATE UNIVERSITY · PI BLASHILL, AARON J · 2012 to 2016
$857k
NIAID NIH HHS 5P30AI060354-08NIAID NIH HHS P30 AI060354NIAID NIH HHS R24 AI067039NIAID NIH HHS R24AI067039NIMH NIH HHS K23 MH096647NIMH NIH HHS K23MH096647NIMH NIH HHS K24 MH094214NIMH NIH HHS R01 MH084759NIMH NIH HHS R01MH084759NIMH NIH HHS T32 MH093310
6 · The paper itself

Abstract

backgroundLow physical activity is associated with depression, which may, in turn, negatively impact antiretroviral therapy (ART) adherence among HIV-infected individuals; however, prior studies have not investigated the relationships between physical inactivity and ART non-adherence. PURPOSE: The purpose of this study was to examine the association of physical inactivity, depression, ART non-adherence, and viral load in HIV-infected men who have sex with men.

methodsThe sample (N = 860) was from a large, multicenter cohort of HIV-infected patients engaged in clinical care.

resultsAcross time, depression mediated the relationship between physical inactivity and ART non-adherence (γ = 0.075) and the relationship between physical inactivity and viral load (γ = 0.05). ART non-adherence mediated the relationship between depression and viral load (γ = 0.002) and the relationship between physical inactivity and viral load (γ = 0.009).

conclusionsLow levels of physical activity predicted increased depression and poor ART adherence over time, which subsequently predicted higher viral load.

Indexed as

Health StatusMotor ActivityAdultDepressionHIV InfectionsHomosexuality, MaleHumansMaleMedication AdherenceProspective StudiesViral Load

Identifiers

PMID23483379
PMCPMC3714319
OpenAlexW2075143542

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.