Evidence map›Paper›PMID 23482914›Full record

Trial reportKorean journal of radiology

CT venography for deep vein thrombosis using a low tube voltage (100 kVp) setting could increase venous enhancement and reduce the amount of administered iodine.

Eun-Suk Cho, Jae-Joon Chung, Sungjun Kim, Joo Hee Kim, Jeong-Sik Yu, Choon-Sik Yoon

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Imaging of acute pulmonary embolism: an update.Cardiovascular diagnosis and therapy · 2018
    Review
  8. Article
  9. Advanced imaging in acute and chronic deep vein thrombosis.Cardiovascular diagnosis and therapy · 2016
    Review
  10. Article
  11. Qualitative evaluation of pulmonary CT angiography findings in pregnant and postpartum women with suspected pulmonary thromboembolism.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eun-Suk ChoDepartment of Radiology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul 135-720, Korea.
Jae-Joon Chung
Sungjun Kim
Joo Hee Kim
Jeong-Sik Yu
Choon-Sik Yoon
Gangnam Severance Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the validity of the 100 kVp setting in CT venography (CTV) in the diagnosis of deep vein thrombosis (DVT), and to evaluate the feasibility of reducing the amount of administered iodine in this setting. MATERIALS AND

methodsAfter receiving the contrast medium (CM) of 2.0 mL/kg, 88 patients underwent CTV of the pelvis and lower extremities by using one of four protocols: Group A, 120 kVp setting and 370 mgI/mL CM; group B, 120 kVp and 300 mgI/mL; group C, 100 kVp and 370 mgI/mL; group D, 100 kVp and 300 mgI/mL. The groups were evaluated for venous attenuation, vein-to-muscle contrast-to-noise ratio (CNR(VEIN)), DVT-to-vein contrast-to-noise ratio (CNR(DVT)), and subjective degree of venous enhancement and image quality.

resultsVenous attenuation and CNR(VEIN) were significantly higher in group C (144.3 Hounsfield unit [HU] and 11.9), but there was no significant difference between group A (118.0 HU and 8.2) and D (122.4 HU and 7.9). The attenuation value of DVT was not significantly different among the four groups, and group C had a higher absolute CNR(DVT) than the other groups. The overall diagnostic image quality and venous enhancement were significantly higher in group C, but there was no difference between groups A and D.

conclusionThe 100 kVp setting in CTV substantially help improve venous enhancement and CNR(VEIN). Furthermore, it enables to reduce the amount of administered iodine while maintaining venous attenuation, as compared with the 120 kVp setting.

Indexed as

Contrast MediaFeasibility StudiesFemaleHumansIohexolLinear ModelsLower ExtremityMaleMiddle AgedPhantoms, ImagingPhlebographyStatistics, NonparametricTomography, X-Ray ComputedVenous ThrombosisContrast MediaIohexoliopromideContrast enhancementContrast mediumCT venographyDeep vein thrombosisLow tube voltage

Identifiers

PMID23482914
PMCPMC3590329
OpenAlexW2102004947

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.