Evidence map›Paper›PMID 23482353›Full record

ArticleAge and ageing2013

Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis.

Igor Akushevich, Julia Kravchenko, Svetlana Ukraintseva, Konstantin Arbeev, Anatoly I Yashin

Open access · bronzeAbstract read
In one paragraph

Article in Age and ageing, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Igor AkushevichCenter for Population Health and Aging, Duke University, Durham, NC 27708, USA.
Julia Kravchenko
Svetlana Ukraintseva
Konstantin Arbeev
Anatoly I Yashin
Center for Child and Family Health · USDuke University · USDuke Medical Center · US

Funding

DYNAMIC DETERMINANTS OF EXCEPTIONAL HEALTH AT LATE AGESR01AG027019 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2006 to 2009
$1.4M
Healthy Life at Risk: The Role of SenescenceR01AG028259 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2005 to 2009
$1.2M
The future of major geriatric disorders in the US elderlyR01AG032319 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2008 to 2012
$1.1M
NIA NIH HHS R01AG027019NIA NIH HHS R01AG028259NIA NIH HHS R01AG032319
6 · The paper itself

Abstract

objectivestime trends of age-adjusted incidence rates of 19 ageing-related diseases were evaluated for 1992-2005 period with the National Long Term Care Survey and the Surveillance, Epidemiology and End RESULTS Registry data both linked to Medicare data (NLTCS-Medicare and SEER-Medicare, respectively).

methodsthe rates were calculated using individual medical histories (34,077 individuals from NLTCS-Medicare and 199,418 from SEER-Medicare) reconstructed using information on diagnoses coded in Medicare data, dates of medical services/procedures and Medicare enrolment/disenrolment.

resultsincreases of incidence rates were dramatic for renal disease [the average annual percent change (APC) is 8.56%, 95% CI = 7.62, 9.50%], goiter (APC = 6.67%, 95% CI = 5, 90, 7, 44%), melanoma (APC = 6.15%, 95% CI = 4.31, 8.02%) and Alzheimer's disease (APC = 3.96%, 95% CI = 2.67, 5.26%), and less prominent for diabetes and lung cancer. Decreases of incidence rates were remarkable for angina pectoris (APC = -6.17%, 95% CI = -6.96, -5.38%); chronic obstructive pulmonary disease (APC = -5.14%, 95% CI = -6.78,-3.47%), and ulcer (APC = -5.82%, 95% CI = -6.77,-4.86%) and less dramatic for carcinomas of colon and prostate, stroke, hip fracture and asthma. Incidence rates of female breast carcinoma, myocardial infarction, Parkinson's disease and rheumatoid arthritis were almost stable. For most diseases, an excellent agreement was observed for incidence rates between NLTCS-Medicare and SEER-Medicare. A sensitivity analysis proved the stability of the evaluated time trends.

conclusiontime trends of the incidence of diseases common in the US elderly population were evaluated. The results show dramatic increase in incidence rates of melanoma, goiter, chronic renal and Alzheimer's disease in 1992-2005. Besides specifying widely recognised time trends on age-associated diseases, new information was obtained for trends of asthma, ulcer and goiter among the older adults in the USA.

Indexed as

AgingAge DistributionAge of OnsetAlzheimer DiseaseAsthmaCardiovascular DiseasesDiabetes MellitusFemaleGoiterHumansIncidenceLeast-Squares AnalysisLinear ModelsLung DiseasesMaleMedicareage-associated diseasecomorbiditydisease onsetMedicareolder peopletime trends

Identifiers

PMID23482353
PMCPMC3684110
OpenAlexW2131221546

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.