ReviewThe Yale journal of biology and medicine2013
The challenges of enrolling older adults into intervention studies.
Review in The Yale journal of biology and medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Ureteroscopy for stone disease in the elderly. is it safe and effective? A systematic review and meta-analysis.World journal of urology · 2025Pooled it
- Non-pharmacological Treatment for Elderly Individuals With Insomnia: A Systematic Review and Network Meta-Analysis.Frontiers in psychiatry · 2020Pooled it
- Strategies to improve engagement of 'hard to reach' older people in research on health promotion: a systematic review.BMC public health · 2017Pooled it
- Systematic Review of the Clinical Application of Exposure Techniques to Community-Dwelling Older Adults with Anxiety.Clinical gerontologistPooled it
- Acupuncture in patients with trigeminal neuralgia-an exploratory mixed methods trial.Frontiers in medicine · 2026Trial
- Success and cost-effectiveness of strategies to recruit older adults to a behavioral intervention research study.Contemporary clinical trials · 2025Trial
- Ecological Predictors of Older Adults' Participation and Retention in a Physical Activity Intervention.International journal of environmental research and public health · 2022Trial
- Trial
- Impact of MyDiabetesPlan, a Web-Based Patient Decision Aid on Decisional Conflict, Diabetes Distress, Quality of Life, and Chronic Illness Care in Patients With Diabetes: Cluster Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Comparison of Recruitment Strategies for Engaging Older Minority Adults: Results From Take Heart.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- A Personalized, Symptom-Based Approach to Boost Research Participation in Hospitalized Older Adults.Journal of the American Geriatrics Society · 2026Article
- Widening participation in cognitive neuroscience: a mixed-methods study of age-related motivators, barriers and attitudes towards imaging methods.BMC medical research methodology · 2026Article
- Gender-related facilitators and barriers to participation in research on aging using fuzzy cognitive mapping.Neurobiology of aging · 2026Article
- Article
- Feasibility and acceptability of two remote physical activity programs for older Latino adults: the C.E.R.E.B.R.O. study, a pilot randomized trial.Frontiers in medicine · 2026Article
- eHealth and the Digital Divide Among Older Canadians: Insights from a National Cross-Sectional Study.Journal of medical Internet research · 2025Article
- Challenges and strategies for spinal cord injury research recruitment in rehabilitation hospitals: a single center perspective.Spinal cord · 2025Review
- Monitoring reaction time to digital device in the very-old to detect early cognitive decline.npj aging · 2024Article
- "Geriatrics (Basel, Switzerland) · 2024Article
- Decentralized study of COVID Vaccine Antibody Response (STOPCoV): Results of a participant satisfaction survey.PLOS digital health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adults aged 65 years or older have been routinely and systematically excluded from research. With the number of older adults at a record high and growing faster than any other age group, there must be an increased priority on meeting the enrollment challenges so intervention studies are relevant to this population. The challenge centers around the complexity and heterogeneity of older adults, leaving a gap between older adults who participate in studies and those who exist in the real world. Barriers to enrollment stem from both the researcher and participant side. Eight barriers from the research perspective and six from the participant perspective are identified and discussed. Solutions to these barriers can be approached from a three-tier framework. The lowest tier is direct solutions to problems, the middle involves support from funders and journals, and the top tier considers a comprehensive view of sampling and design decisions.
Indexed as
Identifiers
23482244PMC3584494What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.