Evidence map›Paper›PMID 23481104›Full record

ReviewPediatric clinics of North America2013

Congenital cytomegalovirus infection: new prospects for prevention and therapy.

Elizabeth C Swanson, Mark R Schleiss

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 213 citations in OpenAlex.

  1. Article
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  12. Article
  13. Cytomegalovirus and Pregnancy: A Narrative Review.Journal of clinical medicine · 2024
    Review
  14. Cytomegalovirus and pregnancy: current evidence for clinical practice.Revista da Associacao Medica Brasileira (1992) · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth C SwansonDivision of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Mark R Schleiss
University of Minnesota Medical Center · US

Funding

Viral Immunomodulation and Rational CMV Vaccine DesignR01HD044864 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI GEBALLE, ADAM P., MCVOY, MICHAEL A · 2003 to 2015
$4.5M
VACCINES FOR PREVENTION OF EXPERIMENTAL CONGENITAL CMVR01HD038416 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHLEISS, MARK R. · 2000 to 2009
$2.2M
Bedside-to-Bench Research Training for Pediatric Infectious Diseases FellowsT32HD068229 · NICHD · UNIVERSITY OF MINNESOTA · PI SCHLEISS, MARK R. · 2011 to 2015
$650k
NICHD NIH HHS HD038416NICHD NIH HHS HD068229NICHD NIH HHS R01 HD038416NICHD NIH HHS R01 HD044864NICHD NIH HHS T32 HD068229
6 · The paper itself

Abstract

Cytomegalovirus is the commonest congenital viral infection in the developed world, with an overall prevalence of approximately 0.6%. Approximately 10% of congenitally infected infants have signs and symptoms of disease at birth, and these symptomatic infants have a substantial risk of subsequent neurologic sequelae. These include sensorineural hearing loss, mental retardation, microcephaly, development delay, seizure disorders, and cerebral palsy. Antiviral therapy for children with symptomatic congenital cytomegalovirus infection is effective at reducing the risk of long-term disabilities and should be offered to families with affected newborns. An effective preconceptual vaccine against CMV could protect against long-term neurologic sequelae and other disabilities.

Indexed as

AlgorithmsAntiviral AgentsChildChild, PreschoolClinical Trials as TopicCytomegalovirusCytomegalovirus InfectionsCytomegalovirus VaccinesDevelopmental DisabilitiesDiagnosis, DifferentialGanciclovirHearing Loss, SensorineuralHumansInfantInfant, NewbornIntellectual DisabilityAntiviral AgentsCytomegalovirus VaccinesGanciclovir

Identifiers

PMID23481104
PMCPMC3807860
OpenAlexW1543773636

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.