Evidence map›Paper›PMID 23481033›Full record

ArticleMedical care2013

Intended versus inferred management after PET for cancer restaging: analysis of Medicare claims linked to a coverage with evidence development registry.

Bruce E Hillner, Tor D Tosteson, Anna N A Tosteson, Qianfei Wang, Yunjie Song, Tracy Onega, Lucy G Hanna, Barry A Siegel

Registry-linked trialAbstract read
In one paragraph

Article in Medical care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00868582 (The National Oncologic PET Registry), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00868582 unknown statusnot on this map

The National Oncologic PET Registry

TypeobservationalSponsorAmerican College of Radiology Imaging NetworkRan2006 to 2021Enrolled333,000ConditionsCancerArmsPET scanning in cancer
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Intended Versus Inferred Treatment AfterJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  2. Impact ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  3. Geographic access to breast imaging for US women.Journal of the American College of Radiology : JACR · 2014
    Article
  4. Intended versus inferred care after PET performed for initial staging in the National Oncologic PET Registry.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bruce E HillnerDepartment of Internal Medicine and the Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA. Hillner@vcu.edu
Tor D Tosteson
Anna N A Tosteson
Qianfei Wang
Yunjie Song
Tracy Onega
Lucy G Hanna
Barry A Siegel

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Comparative Effectiveness of Advanced Imaging in CancerRC2CA148259 · NCI · DARTMOUTH COLLEGE · PI BLACK, WILLIAM C, HILLNER, BRUCE ELLIS · 2009 to 2009
$2.0M
NCI NIH HHS P30 CA023108NCI NIH HHS RC2 CA148259NCI NIH HHS RC2CA148259
6 · The paper itself

Abstract

backgroundThe National Oncologic PET Registry (NOPR) ascertained changes in the intended management of cancer patients using questionnaire data obtained before and after positron emission tomography (PET) under Medicare's coverage with evidence development policy.

objectiveTo assess the concordance between intended care plans and care received as ascertained through administrative claims data. RESEARCH

designAnalysis of linked data of NOPR participants from 2006 to 2008 and their corresponding Medicare claims. SUBJECTS: Consenting patients aged older than 65 years having their first PET for restaging of bladder, kidney, ovarian, pancreas, prostate, small cell lung, or stomach cancer. MEASURES: : Agreement (positive predictive values and κ) between NOPR post-PET intended management plans for treatment (systemic therapy, radiotherapy, surgery, or combinations), biopsy, or watching as compared to claims-inferred care 30 days after PET.

resultsA total of 8460 patients with linked data were assessed. A total of 43.5% had metastatic disease and 45.3% had treatment planned (predominantly systemic therapy only), 11.1% biopsy and 43.5% watching. Claims-confirmed intended plans (positive predictive value) for single-mode systemic therapy in 62.0%, radiation in 66.0%, surgery in 45.6%, and biopsy in 55.7%. A total of 25.7% of patients with a plan of watching had treatment claims. By cancer type, κ ranged for systemic therapy only from 0.17 to 0.40 and for watching from 0.21 to 0.41. Agreement rates varied by cancer types but were minimally associated with patient age, performance status, comorbidity, or stage.

conclusionsAmong elderly cancer patients undergoing PET for restaging, there was moderate concordance between their physicians' planned management and claims-inferred actions within a narrow time window. When higher accuracy levels are required in future coverage with evidence development studies, alternative designs will be needed.

Indexed as

MedicareAgedAged, 80 and overBiopsyEvidence-Based MedicineFemaleHumansInsurance Claim ReviewMaleNeoplasmsNeoplasm StagingOutcome and Process Assessment, Health CarePositron-Emission TomographyRegistriesRetrospective StudiesSurveys and Questionnaires

Identifiers

PMID23481033
PMCPMC3662234

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.