Evidence map›Paper›PMID 23479752›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2013

Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases.

Laura A Hug, Farai Maphosa, David Leys, Frank E Löffler, Hauke Smidt, Elizabeth A Edwards, Lorenz Adrian

Open access · bronzeAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 308 citations in OpenAlex.

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  17. Pangenomic insights intoMicrobial genomics · 2024
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  18. Article
  19. FromApplied and environmental microbiology · 2024
    Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Laura A HugDepartment of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.
Farai Maphosa
David Leys
Frank E Löffler
Hauke Smidt
Elizabeth A Edwards
Lorenz Adrian
University of Toronto · CAWageningen University & Research · NLHelmholtz Centre for Environmental Research · DEUniversity of Manchester · GBUniversity of Tennessee at Knoxville · US

Funding

Biotechnology and Biological Sciences Research Council BB/C00521X/1
6 · The paper itself

Abstract

Organohalide respiration is an anaerobic bacterial respiratory process that uses halogenated hydrocarbons as terminal electron acceptors during electron transport-based energy conservation. This dechlorination process has triggered considerable interest for detoxification of anthropogenic groundwater contaminants. Organohalide-respiring bacteria have been identified from multiple bacterial phyla, and can be categorized as obligate and non-obligate organohalide respirers. The majority of the currently known organohalide-respiring bacteria carry multiple reductive dehalogenase genes. Analysis of a curated set of reductive dehalogenases reveals that sequence similarity and substrate specificity are generally not correlated, making functional prediction from sequence information difficult. In this article, an orthologue-based classification system for the reductive dehalogenases is proposed to aid integration of new sequencing data and to unify terminology.

Indexed as

Genes, BacterialBacterial ProteinsDatabases, GeneticDesulfitobacteriumElectron TransportHydrocarbons, HalogenatedHydrolasesPhylogenyRNA, Ribosomal, 16SSpecies SpecificitySubstrate SpecificityBacterial ProteinsHydrocarbons, HalogenatedHydrolasesRNA, Ribosomal, 16S

Identifiers

PMID23479752
PMCPMC3638463
OpenAlexW2141606648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.