Trial reportProceedings of the National Academy of Sciences of the United States of America2013
Portraying the unique contribution of the default mode network to internally driven mnemonic processes.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed.
- The effects of Pythagorean Self-Awareness Intervention on breast cancer patients undergoing adjuvant therapy: A pilot randomized controlled trial.Breast (Edinburgh, Scotland) · 2020Trial
- Distinct neural signatures of phonemic and semantic verbal fluency: a double dissociation in cortical activation and functional connectivity revealed by fNIRS.Neurophotonics · 2026Article
- Episodic Memory, Chiari I Malformation, Personality and Coping: The Role of Chronic Pain.Behavioral sciences (Basel, Switzerland) · 2025Review
- Integrating gut microbiome and neuroplasticity genomics in alcohol use disorder therapy.Human genomics · 2025Observational
- Default mode network activation at task switches reflects mental task-set structure.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Altered Expression of Neuroplasticity-Related Genes in Alcohol Addiction and Treatment.International journal of molecular sciences · 2024Article
- Processing of social closeness in the human brain.Communications biology · 2024Article
- Same, Same but Different? A Multi-Method Review of the Processes Underlying Executive Control.Neuropsychology review · 2024Review
- How does the "default mode" network contribute to semantic cognition?Brain and language · 2024Review
- Intrinsic functional connectivity strength of SuperAgers in the default mode and salience networks: Insights from ADNI.Aging brain · 2024Article
- Replicable Patterns of Memory Impairments in Children With Autism and Their Links to Hyperconnected Brain Circuits.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Attentional switch to memory: An early and critical phase of the cognitive cascade allowing autobiographical memory retrieval.Psychonomic bulletin & review · 2023Review
- Neurofunctional underpinnings of individual differences in visual episodic memory performance.Nature communications · 2023Article
- Pythagorean Self-Awareness Intervention Promoted Healthy Dietary Patterns, Controlled Body Mass Index, and Reduced Self-Reported Stress Levels of Primary School Children: Α One-Arm Pilot Study.Advances in experimental medicine and biology · 2023Article
- Functional brain networks underlying the interaction between central and peripheral processes involved in Chinese handwriting in children and adults.Human brain mapping · 2023Article
- Deficient Novelty Detection and Encoding in Early Alzheimer's Disease: An ERP Study.Brain topography · 2022Article
- Functional Neural Correlates of Semantic Fluency Task Performance in Mild Cognitive Impairment and Alzheimer's Disease: An FDG-PET Study.Journal of Alzheimer's disease : JAD · 2022Article
- The Unique Fiber Anatomy of Middle Temporal Gyrus Default Mode Connectivity.Operative neurosurgery (Hagerstown, Md.) · 2021Article
- Brain dysconnectivity relates to disability and cognitive impairment in multiple sclerosis.Human brain mapping · 2021Article
- A Gradient of Sharpening Effects by Perceptual Prior across the Human Cortical Hierarchy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous neuroimaging studies have implicated default mode network (DMN) involvement in both internally driven processes and memory. Nevertheless, it is unclear whether memory operations reflect a particular case of internally driven processing or alternatively involve the DMN in a distinct manner, possibly depending on memory type. This question is critical for refining neurocognitive memory theorem in the context of other endogenic processes and elucidating the functional significance of this key network. We used functional MRI to examine DMN activity and connectivity patterns while participants overtly generated words according to nonmnemonic (phonemic) or mnemonic (semantic or episodic) cues. Overall, mnemonic word fluency was found to elicit greater DMN activity and stronger within-network functional connectivity compared with nonmnemonic fluency. Furthermore, two levels of functional organization of memory retrieval were shown. First, across both mnemonic tasks, activity was greater mainly in the posterior cingulate cortex, implying selective contribution to generic aspects of memory beyond its general involvement in endogenous processes. Second, parts of the DMN showed distinct selectivity for each of the mnemonic conditions; greater recruitment of the anterior prefrontal cortex, retroesplenial cortex, and hippocampi and elevated connectivity between anterior and posterior medial DMN nodes characterized the semantic condition, whereas increased recruitment of posterior DMN components and elevated connectivity between them characterized the episodic condition. This finding emphasizes the involvement of DMN elements in discrete aspects of memory retrieval. Altogether, our results show a specific contribution of the DMN to memory processes, corresponding to the specific type of memory retrieval.
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