ArticleApplied physics letters2013
Breaking the acoustic diffraction limit via nonlinear effect and thermal confinement for potential deep-tissue high-resolution imaging.
Article in Applied physics letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Noninvasive measurement of local temperature using ultrasound-switchable fluorescence.Biomedical optics express · 2023Article
- Thermo- and pH-sensitive nanoparticles of poly (Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Article
- An ICCD camera-based time-domain ultrasound-switchable fluorescence imaging system.Scientific reports · 2019Article
- In vivo ultrasound-switchable fluorescence imaging.Scientific reports · 2019Article
- Newly-Engineered Materials for Bio-Imaging Technology: A Focus on the Hybrid System of Ultrasound and Fluorescence.Frontiers in bioengineering and biotechnology · 2019Review
- A Dual-Modality System for Both Multi-Color Ultrasound-Switchable Fluorescence and Ultrasound Imaging.International journal of molecular sciences · 2017Article
- Simulation-based evaluation of the resolution and quantitative accuracy of temperature-modulated fluorescence tomography.Applied optics · 2015Article
- High resolution imaging beyond the acoustic diffraction limit in deep tissue via ultrasound-switchable NIR fluorescence.Scientific reports · 2014Article
- Development of Ultrasound-switchable Fluorescence Imaging Contrast Agents based on Thermosensitive Polymers and Nanoparticles.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Our recently developed ultrasound-switchable fluorescence (USF) imaging technique showed that it was feasible to conduct high-resolution fluorescence imaging in a centimeter-deep turbid medium. Because the spatial resolution of this technique highly depends on the ultrasound-induced temperature focal size (UTFS), minimization of UTFS becomes important for further improving the spatial resolution USF technique. In this study, we found that UTFS can be significantly reduced below the diffraction-limited acoustic intensity focal size via nonlinear acoustic effects and thermal confinement by appropriately controlling ultrasound power and exposure time, which can be potentially used for deep-tissue high-resolution imaging.
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Registered trials
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