Evidence map›Paper›PMID 23479075›Full record

ArticleJournal of autism and developmental disorders2013

Parental age and risk of autism spectrum disorders in a Finnish national birth cohort.

Katja M Lampi, Susanna Hinkka-Yli-Salomäki, Venla Lehti, Hans Helenius, Mika Gissler, Alan S Brown, Andre Sourander

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Review
  6. Rethinking advanced motherhood: a new ethical narrative.Medicine, health care, and philosophy · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Effect of advanced parental age on pregnancy outcome and offspring health.Journal of assisted reproduction and genetics · 2022
    Review
  11. Association between paternal age at childbirth and autism spectrum disorder in offspring.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Katja M LampiDepartment of Child Psychiatry, University of Turku, Turku, Finland.
Susanna Hinkka-Yli-Salomäki
Venla Lehti
Hans Helenius
Mika Gissler
Alan S Brown
Andre Sourander
University of Turku · FIColumbia University · US

Funding

Medical Research Council MR/K006525/1
6 · The paper itself

Abstract

Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger's syndrome (n = 1,785) or other pervasive developmental disorder (PDD) (n = 1,796), which were ascertained from the Finnish Hospital Discharge Register. Controls were selected from the Finnish Medical Birth Register. Conditional logistic regression models were used for statistical analyses. Advanced paternal age (35-49 years) was associated with childhood autism in offspring, whereas advanced maternal age was associated with both Asperger's syndrome and PDD in offspring (35 years or more and 40 years or more, respectively). Teenage motherhood (19 years or less) was associated with PDD in offspring. The main finding was that maternal and paternal ages were differentially associated with ASD subtypes. In addition to advanced parental age, teenage pregnancy seems to incur a risk for PDD in offspring.

Indexed as

Maternal AgeParentsPaternal AgeAdolescentAdultAgedCase-Control StudiesChildChild Development Disorders, PervasiveChild, PreschoolFemaleFinlandHumansLogistic ModelsMaleMiddle Aged

Identifiers

PMID23479075
OpenAlexW1999357826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.