ArticleAntimicrobial agents and chemotherapy2013
Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma.
Article in Antimicrobial agents and chemotherapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026Review
- Biological cost of aminoglycoside resistance Arm/Kam 16S rRNA methyltransferases from natural antibiotic producers and clinical pathogens.Antimicrobial agents and chemotherapy · 2025Article
- The relationship between virulence and drug resistance genes inFrontiers in cellular and infection microbiology · 2025Article
- Genomic Characterization of 16S rRNA Methyltransferase-ProducingAntibiotics (Basel, Switzerland) · 2024Article
- Ribosome-targeting antibiotics and resistanceRSC medicinal chemistry · 2023Review
- Research Updates of Plasmid-Mediated Aminoglycoside Resistance 16S rRNA Methyltransferase.Antibiotics (Basel, Switzerland) · 2022Review
- Functional and Structural Characterization of Acquired 16S rRNA Methyltransferase NpmB1 Conferring Pan-Aminoglycoside Resistance.Antimicrobial agents and chemotherapy · 2021Article
- Prevalence of 16S rRNA Methylation Enzyme GeneFrontiers in microbiology · 2021Article
- Aminoglycoside Resistance: Updates with a Focus on Acquired 16S Ribosomal RNA Methyltransferases.Infectious disease clinics of North America · 2020Review
- Expansion of acquired 16S rRNA methytransferases along with CTX-M-15, NDM and OXA-48 within three sequence types of Escherichia coli from northeast India.BMC infectious diseases · 2020Article
- Molecular Characterization of Multidrug-ResistantAntimicrobial agents and chemotherapy · 2019Article
- Article
- A New Variant of 16S rRNA Methylase, RmtD3, in a Clinical Isolate of Pseudomonas aeruginosa in Myanmar.Antimicrobial agents and chemotherapy · 2018Article
- Destination of aminoglycoside antibiotics in the 'post-antibiotic era'.The Journal of antibiotics · 2017Review
- Pseudomonas aeruginosa Clinical Isolates in Nepal Coproducing Metallo-β-Lactamases and 16S rRNA Methyltransferases.Antimicrobial agents and chemotherapy · 2017Article
- Inventory of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in France as Assessed by a Multicenter Study.Antimicrobial agents and chemotherapy · 2017Article
- Clonal Spread of 16S rRNA Methyltransferase-ProducingFrontiers in microbiology · 2017Article
- Prevalence of carbapenemases among high-level aminoglycoside-resistantExperimental and therapeutic medicine · 2016Article
- NDM-1 and rmtC-ProducingJundishapur journal of microbiology · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Klebsiella pneumoniae strain MRSN2404 was isolated from the chronic wound of a soldier who had been wounded in Iraq in 2006. The strain displayed very high MICs of all aminoglycosides, including arbekacin. A gene encoding a novel 16S rRNA methyltransferase, now designated RmtH, was identified. RmtH had 64% identity with RmtB1 and RmtB2. rmtH was bracketed by two copies of ISCR2, which may have played a role in its mobilization.
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Registered trials
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