ReviewCurrent opinion in cell biology2013
ER structure and function.
Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
134 citing papers in PubMed, 213 citations in OpenAlex.
- Atg39-dependent nucleophagy and Atg40-dependent ER-phagy require the Apq12/Brr6/Brl1 complex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Noncentrosomal Microtubule Assembly and Its Regulation.Cytoskeleton (Hoboken, N.J.) · 2026Review
- Polymeric nanocarriers for subcellular targeting in photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Review
- Coupling of cargo to the autophagy receptor is a critical step in ER-phagy.Science advances · 2026Article
- Understanding the Mechanisms of Supported Lipid Membranes Reshaping into Tubular Networks Using Quantitative DIC Microscopy.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Zinc as a master regulator of intracellular organelle homeostasis.Experimental & molecular medicine · 2026Review
- RanBP2-dependent annulate lamellae drive nuclear pore assembly and nuclear expansion.Nature communications · 2026Article
- Pan-cancer analysis reveals differential PERK expression across tumour types and its potential as a therapeutic target.Discover oncology · 2026Article
- The Influence of Sex and Hormones on Organelle Stress in Kidney Injury: Insights from Preclinical Models.Biology · 2026Review
- AGPAT2 acts at the crossroads of lipid biosynthesis and DRP1-mediated ER morphogenesis.Nature communications · 2025Article
- Integrated multi-omics analysis reveals TMEM147 as an immunosuppressive prognostic biomarker in LUAD.Biochemistry and biophysics reports · 2025Article
- Impaired stemness in aging periodontal ligament stem cells is mediated by the progerin/endoplasmic reticulum stress/p53 axis.Journal of advanced research · 2025Article
- Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion.Biochemical Society transactions · 2025Review
- Review
- Orchestration of SARS-CoV-2 Nsp4 and host cell ESCRT proteins induces morphological changes of the endoplasmic reticulum.Molecular biology of the cell · 2025Article
- The Overexpression of RTN4 Significantly Associated With an Unfavourable Prognosis in Patients With Lower-Grade Gliomas.Journal of cellular and molecular medicine · 2025Article
- Signaling Regulation of FAM134-Dependent ER-Phagy in Cells.Journal of cellular physiology · 2025Review
- In Vitro Homotypic ER Membrane Fusion Assay Using Isolated Yeast Microsomes.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Organelle abnormalities in Alzheimer's disease.Organelle (Tucson, Ariz.) · 2025Article
- Legionella uses host Rab GTPases and BAP31 to create a unique ER niche.Cell reports · 2024Article
74 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The ER forms a contiguous structure of interconnected sheets and tubules that spreads from the nuclear envelope to the cell cortex. Through its attachment to the cytoskeleton, the ER undergoes dynamic rearrangements, such as tubule extension and movement. ER shaping proteins (reticulons and DP1/Yop1p) play key roles in generating and maintaining the unique reticular morphology of the ER. Atlastin and its yeast homologue, Sey1p, mediate homotypic ER membrane fusion, which leads to the formation of new three-way junctions within the polygonal network. At these junctions, the Lunapark protein, Lnp1p, works in conjunction with the reticulons, DP1/Yop1p, and in antagonism to atlastin/Sey1p to maintain the network in a dynamic equilibrium. Defects in ER morphology have been linked to certain neurological disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.