Evidence map›Paper›PMID 23477832›Full record

ReviewCurrent opinion in virology2013

Novel vaccine strategies against emerging viruses.

Adolfo García-Sastre, Ignacio Mena

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Various vaccine platforms in the field of COVID-19.Beni-Suef University journal of basic and applied sciences · 2022
    Review
  8. Review
  9. Article
  10. Pathogenic viruses: Molecular detection and characterization.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Evolutionary ecology of virus emergence.Annals of the New York Academy of Sciences · 2017
    Review
  17. Robust antibody and CD8NPJ vaccines · 2017
    Article
  18. Review
  19. Article
  20. Changing face of vaccination in immunocompromised hosts.Current infectious disease reports · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adolfo García-SastreDepartment of Microbiology, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, United States. Adolfo.Garcia-Sastre@mssm.edu
Ignacio Mena

Funding

Toward a Universal Influenza Virus VaccineP01AI097092 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AHMED, RAFI · 2012 to 2022
$17.6M
SUPPLEMENT TO: A Novel approach to RSV vaccinationR01AI088770 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI DURBIN, JOAN E. · 2010 to 2015
$3.7M
NIAID NIH HHS HHSN266200700010CNIAID NIH HHS P01 AI097092NIAID NIH HHS R01 AI088770
6 · The paper itself

Abstract

One of the main public health concerns of emerging viruses is their potential introduction into and sustained circulation among populations of immunologically naïve, susceptible hosts. The induction of protective immunity through vaccination can be a powerful tool to prevent this concern by conferring protection to the population at risk. Conventional approaches to develop vaccines against emerging pathogens have significant limitations: lack of experimental tools for several emerging viruses of concern, poor immunogenicity, safety issues, or lack of cross-protection against antigenic variants. The unpredictability of the emergence of future virus threats demands the capability to rapidly develop safe, effective vaccines. We describe some recent advances in new vaccine strategies that are being explored as alternatives to classical attenuated and inactivated vaccines, and provide examples of potential novel vaccines for emerging viruses. These approaches might be applied to the control of many other emerging pathogens.

Indexed as

BiotechnologyCommunicable Diseases, EmergingDrug DiscoveryHumansTechnology, PharmaceuticalViral VaccinesVirus DiseasesViral Vaccines

Identifiers

PMID23477832
PMCPMC3644304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.