ArticleNeural plasticity2013
Why I am not shy: a reply to Tononi and Cirelli.
Article in Neural plasticity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Local versus global sleep organization and the quest to determine sleep function.Neurobiology of sleep and circadian rhythms · 2025Article
- Unraveling the Mysteries of Sleep: Exploring Phylogenomic Sleep Signals in the Recently Characterized Archaeal Phylum Lokiarchaeota near Loki's Castle.International journal of molecular sciences · 2024Article
- Article
- The Ontogenesis of Mammalian Sleep: Form and Function.Current sleep medicine reports · 2020Article
- Self-organized reactivation maintains and reinforces memories despite synaptic turnover.eLife · 2019Article
- Slow-Wave Activity Enhancement to Improve Cognition.Trends in neurosciences · 2018Review
- Sleep research goes wild: new methods and approaches to investigate the ecology, evolution and functions of sleep.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Pleiotropic genetic effects influencing sleep and neurological disorders.The Lancet. Neurology · 2017Review
- Linking Network Activity to Synaptic Plasticity during Sleep: Hypotheses and Recent Data.Frontiers in neural circuits · 2017Review
- Circadian Regulation of Synaptic Plasticity.Biology · 2016Review
- Sleep and synaptic plasticity in the developing and adult brain.Current topics in behavioral neurosciences · 2015Review
- Sleep, clocks, and synaptic plasticity.Trends in neurosciences · 2014Review
- Sleep memory processing: the sequential hypothesis.Frontiers in systems neuroscience · 2014Article
- Sleep, plasticity and memory from molecules to whole-brain networks.Current biology : CB · 2013Review
- Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress.Frontiers in behavioral neuroscience · 2013Review
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
Abstract
In a recent article I reviewed an influential theory of sleep function, the "synaptic homeostasis hypothesis (SHY.)" According to SHY, sleep renormalizes synapses that are potentiated during prior wakefulness. I concluded that while SHY is a seminal theory with important implications about sleep function and the brain, its underlying mechanisms are poorly defined. In an accompanying article, the authors of SHY responded at length. Their reply is thoughtful and provocative, but unfortunately many of the points I raised were not accurately represented or addressed. In this brief commentary, I attempt to clarify some points of confusion. I also explain why any theory of sleep function is incomplete without an understanding of the underlying cellular mechanisms.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.