ArticleCritical care research and practice2013
Role of new biomarkers: functional and structural damage.
Article in Critical care research and practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Article
- Salidroside protects against high-altitude hypoxia-induced kidney injury via regulation of renal dopamine D1-like receptors.PloS one · 2026Article
- Exosomes derived from human umbilical cord mesenchymal stem cells ameliorate AKI after cardiac surgery by facilitating miR-21-5p targeting TEAD1.Renal failure · 2025Article
- Advancements in Trauma-Induced Acute Kidney Injury: Diagnostic and Therapeutic Innovations.Life (Basel, Switzerland) · 2024Review
- Radiation nephropathy: Mechanisms of injury and recovery in a murine model.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
- Selected biochemical parameters in the urine of HIV-infected patients in monitoring of kidney function.Archives of medical science : AMS · 2023Article
- Early diagnostic biomarkers for acute kidney injury using cisplatin-induced nephrotoxicity in rat model.Current research in toxicology · 2023Article
- PASS: A scoring system to evaluate persistent kidney injury in critically ill ICU adult patients.F1000Research · 2023Article
- Burn-Induced Acute Kidney Injury-Two-Lane Road: From Molecular to Clinical Aspects.International journal of molecular sciences · 2022Review
- Acute kidney injury in pediatric hematopoietic cell transplantation: critical appraisal and consensus.Pediatric nephrology (Berlin, Germany) · 2022Review
- Baseline serum cystatin C as a marker of acute kidney injury in patients with acute-on-chronic liver failure.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Observational
- Article
- Rapid and sensitive detection of L-FABP for prediction and diagnosis of acute kidney injury in critically ill patients by chemiluminescent immunoassay.Journal of clinical laboratory analysis · 2021Article
- Quantitative Analysis of Microperfusion in Contrast-Induced Nephropathy Using Contrast-Enhanced Ultrasound: An Animal Study.Korean journal of radiology · 2021Article
- Urinary Neutrophil Gelatinase-Associated Lipocalin as a Marker of Urinary Tract Obstruction in Newborns with Congenital Unilateral Urinary Tract Dilatation.Indian journal of pediatrics · 2021Article
- Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology procedures.International urology and nephrology · 2020Article
- NGAL, albumin and cystatin C during cisplatin therapy.Physiological research · 2020Article
- The Predictive Role of the Biomarker Kidney Molecule-1 (KIM-1) in Acute Kidney Injury (AKI) Cisplatin-Induced Nephrotoxicity.International journal of molecular sciences · 2019Review
- Urinary neutrophil gelatinase-associated lipocalin as a biomarker to monitor renal function in patients with obstructive ureteral calculi.World journal of urology · 2019Article
- [Diagnostic value of serum cystatin C and neutrophil gelatinase-associated lipocalin level in patients with acute renal injury secondary to cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional diagnosis of acute kidney injury (AKI) depends on detection of oliguria and rise of serum creatinine level, which is an unreliable and delayed marker of kidney damage. Delayed diagnosis of AKI in the critically ill patient is related to increased morbidity and mortality, prolonged length of stay, and cost escalation. The discovery of a reliable biomarker for early diagnosis of AKI would be very helpful in facilitating early intervention, evaluating the effectiveness of therapy, and eventually reducing cost and improving outcome. Innovative technologies such as genomics and proteomics have contributed to the discovery of new biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys C), kidney injury molecule-1 (KIM-1), interleukin-18 (IL-18), and liver-type fatty acid binding protein (L-FABP). The current status of the most promising of these novel AKI biomarkers, including NGAL, Cys C, KIM-1, L-FABP, and IL-18, is reviewed.
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Registered trials
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