Evidence map›Paper›PMID 23476712›Full record

ArticleSoft matter2013

Stacking of Short DNA Induces the Gyroid Cubic-to-Inverted Hexagonal Phase Transition in Lipid-DNA Complexes.

Cecília Leal, Kai K Ewert, Nathan F Bouxsein, Rahau S Shirazi, Youli Li, Cyrus R Safinya

Open access · greenAbstract read
In one paragraph

Article in Soft matter, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Boosting Lipofection Efficiency Through Enhanced Membrane Fusion Mechanisms.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. 3D Columnar Phase of Stacked Short DNA Organized by Coherent Membrane Undulations.Langmuir : the ACS journal of surfaces and colloids · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Self-organization of Nucleic Acids in Lipid Constructs.Current opinion in colloid & interface science · 2016
    Article
  16. Cationic liposome-nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cecília LealPhysics, Materials, and Molecular, Cellular & Developmental Biology Departments, University of California, Santa Barbara, California 93106, United States.
Kai K Ewert
Nathan F Bouxsein
Rahau S Shirazi
Youli Li
Cyrus R Safinya
University of California, Santa Barbara · US

Funding

Structures of Lipid-DNA Nonviral Gene Delivery Systems 4R01GM059288 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SAFINYA, CYRUS R · 1999 to 2016
$4.2M
NIGMS NIH HHS R01 GM059288
6 · The paper itself

Abstract

Lyotropic phases of amphiphiles are a prototypical example of self-assemblies. Their structure is generally determined by amphiphile shape and their phase transitions are primarily governed by composition. In this paper, we demonstrate a new paradigm for membrane shape control where the electrostatic coupling of charged membranes to short DNA (sDNA), with tunable temperature-dependent end-to-end stacking interactions, enables switching between the inverted gyroid cubic structure (Q

Identifiers

PMID23476712
PMCPMC3587977
OpenAlexW2054192864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.