ArticleEvidence-based complementary and alternative medicine : eCAM2013
Acupressure at the Meridian Acupoint Xiyangguan (GB33) Influences Near-Infrared Spectroscopic Parameters (Regional Oxygen Saturation) in Deeper Tissue of the Knee in Healthy Volunteers.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study on the Metabolic Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris
Difference in the Metabolic Characteristics of COPD Patients and Healthy Adults
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Effectiveness of Acupotomy Combined with Topical Diclofenac for Knee Osteoarthritis: A Randomized Controlled Trial.Journal of pain research · 2025Trial
- Difference in the metabolic characteristics of chronic obstructive pulmonary disease patients and healthy adults.Medicine · 2020Trial
- A case report of superficial temporal artery aneurysm associated with acupressure massage.Surgical neurology international · 2026Article
- Acupressure in patients with seasonal allergic rhinitis: a randomized controlled exploratory trial.Chinese medicine · 2021Article
- Intrarater and Interrater Reliability of Infrared Image Analysis of Forearm Acupoints before and after Moxibustion.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Multimodal Laser Stimulation and Traditional Needle Acupuncture in Post-Stroke Patients-A Pilot Cross-Over Study with Results from Near Infrared Spectroscopy.Medicines (Basel, Switzerland) · 2019Article
- Contemporary acupressure therapy: Adroit cure for painless recovery of therapeutic ailments.Journal of traditional and complementary medicine · 2017Review
- The Effects of Acupuncture on Cerebral and Muscular Microcirculation: A Systematic Review of Near-Infrared Spectroscopy Studies.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- RegentK and Physiotherapy-Electrodermal Mapping.Medicines (Basel, Switzerland) · 2014Article
- Temperature Measurements in Rehabilitation in Patients with Completely Ruptured Anterior Cruciate Ligament before and after RegentK and Physiotherapy.Medicines (Basel, Switzerland) · 2014Article
- Manual khalifa therapy improves functional and morphological outcome of patients with anterior cruciate ligament rupture in the knee: a randomized controlled trial.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Manual khalifa therapy in patients with completely ruptured anterior cruciate ligament in the knee: first preliminary results from thermal imaging.North American journal of medical sciences · 2013Article
- Manual khalifa therapy in patients with completely ruptured anterior cruciate ligament in the knee: first results from near-infrared spectroscopy.North American journal of medical sciences · 2013Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Up to now, it is still unknown whether microcirculation of deeper peripheral tissue (knee) can be modulated by acupuncture or acupressure on a meridian acupoint. The goal of this pilot study was to investigate possible effects of acupressure at the Xiyangguan acupoint (GB33) on the regional oxygen saturation of the deeper knee tissues by near-infrared spectroscopy (NIRS). Twelve healthy volunteers with a mean age of 23.8 ± 1.6 years were investigated. Acupressure stimulation was performed for 5 minutes at the Xiyangguan acupoint. The results of the controlled study showed a significant increase of the values of regional oxygen saturation on the stimulated side of the knee (P = 0.033), whereas the opposite side on the same knee showed insignificant changes. These results may serve as a valuable basis for monitoring a possible therapeutic effect (e.g., after Khalifa therapy) in patients with knee problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.