Evidence map›Paper›PMID 23475618›Full record

ArticleApplied and environmental microbiology2013

Genetic evidence for a molybdopterin-containing tellurate reductase.

Joanne Theisen, Gerben J Zylstra, Nathan Yee

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The role of cysteine in tellurate reduction and toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021
    Article
  6. Impact of Tellurite on the Metabolism ofFrontiers in microbiology · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joanne TheisenSchool of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, USA.
Gerben J Zylstra
Nathan Yee
Rutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic identity and cofactor composition of the bacterial tellurate reductase are currently unknown. In this study, we examined the requirement of molybdopterin biosynthesis and molybdate transporter genes for tellurate reduction in Escherichia coli K-12. The results show that mutants deleted of the moaA, moaB, moaE, or mog gene in the molybdopterin biosynthesis pathway lost the ability to reduce tellurate. Deletion of the modB or modC gene in the molybdate transport pathway also resulted in complete loss of tellurate reduction activity. Genetic complementation by the wild-type sequences restored tellurate reduction activity in the mutant strains. These findings provide genetic evidence that tellurate reduction in E. coli involves a molybdoenzyme.

Indexed as

Gene Expression Regulation, EnzymologicCoenzymesEnzyme ActivationEscherichia coli K12Escherichia coli ProteinsGene DeletionGene Expression Regulation, BacterialGenes, BacterialGenetic Complementation TestMetalloproteinsMolybdenum CofactorsProtein TransportPteridinesSulfurtransferasesTelluriumCoenzymesEscherichia coli ProteinsMetalloproteinsMoaB protein, E coliMog protein, E coliMolybdenum Cofactorsmolybdopterinmolybdopterin synthasePteridinesSulfurtransferasesTelluriumtellurous acid

Identifiers

PMID23475618
PMCPMC3685252
OpenAlexW2080832779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.