Evidence map›Paper›PMID 23475599›Full record

ReviewCurrent gastroenterology reports2013

Ambulatory reflux monitoring in GERD--which test should be performed and should therapy be stopped?

Andrew J Gawron, John E Pandolfino

Open access · greenAbstract readReview
In one paragraph

Review in Current gastroenterology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Quality of Care for Gastroesophageal Reflux Disease.Digestive diseases and sciences · 2017
    Review
  5. Chronic cough: a gastroenterology perspective.Current opinion in otolaryngology & head and neck surgery · 2013
    Review
  6. Article
  7. pH Scores in Hiatal Repair with Transoral Incisionless Fundoplication.JSLS : Journal of the Society of Laparoendoscopic Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew J GawronDepartment of Medicine, The Feinberg School of Medicine, Northwestern University, 676 St Clair St, Suite 1400, Chicago, IL 60611-2951, USA.
John E Pandolfino
Northwestern University · US

Funding

NRSA INSTITUTIONAL TRAINING GRANTT32HS000078 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOLL, JANE LOUISE · 1998 to 2018
$5.6M
The mechanics of symptom generation in dysphagiaR01DK079902 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2009 to 2017
$2.9M
AHRQ HHS T-32 HS 000078AHRQ HHS T32 HS000078NIDDK NIH HHS R01 DK079902
6 · The paper itself

Abstract

Diagnosing gastroesophageal reflux disease (GERD) often entails using a combination of patient symptoms, response to proton pump inhibitors (PPI), upper endoscopy, and ambulatory reflux testing. Each of these has limitations of which the clinician must be aware when managing patients with reflux symptoms. Ambulatory reflux monitoring, in particular, can potentially document the true presence of pathologic GERD. Consequently, reflux testing is often necessary in our evaluation of patients with reflux symptoms, and can be useful in distinguishing etiologies driving a lack of response to PPI therapy. Reflux testing results can be also used to guide appropriate PPI prescribing and clinical decision making for appropriate or unnecessary therapy. This review focuses on the limitations of our current diagnostic paradigm and highlights how reflux testing can be helpful in the diagnosis and management of patients with poor response to PPI therapy.

Indexed as

Esophageal pH MonitoringAlgorithmsEndoscopy, GastrointestinalGastroesophageal RefluxHumansMonitoring, AmbulatoryProton Pump InhibitorsTreatment FailureProton Pump Inhibitors

Identifiers

PMID23475599
PMCPMC3626104
OpenAlexW1966265722

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.