ReviewLab on a chip2013
Microfluidic systems for studying neurotransmitters and neurotransmission.
Review in Lab on a chip, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Lipid Rafts: The Maestros of Normal Brain Development.Biomolecules · 2024Review
- Monitoring hormone and small molecule secretion dynamics from islets-on-chip.Analytical and bioanalytical chemistry · 2023Article
- Stimulation of Local Cytosolic Calcium Release by Photothermal Heating for Studying Intra- and Intercellular Calcium Waves.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- "Chip-on-a-Transwell" Devices for User-Friendly Control of the Microenvironment of Cultured Cells.ACS applied bio materials · 2019Article
- Review
- Integrating Mass Spectrometry with Microphysiological Systems for Improved Neurochemical Studies.Microphysiological systems · 2018Article
- Microfabricated Probes for Studying Brain Chemistry: A Review.Chemphyschem : a European journal of chemical physics and physical chemistry · 2018Review
- Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Review
- A neuron-in-capillary platform for facile collection and mass spectrometric characterization of a secreted neuropeptide.Scientific reports · 2016Article
- Microfluidic Platform with In-Chip Electrophoresis Coupled to Mass Spectrometry for Monitoring Neurochemical Release from Nerve Cells.Analytical chemistry · 2016Article
- An open-chamber flow-focusing device for focal stimulation of micropatterned cells.Biomicrofluidics · 2016Article
- A Microfluidic Platform for Long-Term Monitoring of Algae in a Dynamic Environment.ACS synthetic biology · 2016Article
- Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System.Journal of the American Society for Mass Spectrometry · 2015Article
- Peptidomics for the discovery and characterization of neuropeptides and hormones.Trends in pharmacological sciences · 2015Review
- Subcellular optogenetics - controlling signaling and single-cell behavior.Journal of cell science · 2015Review
- Microelectronics-based biosensors dedicated to the detection of neurotransmitters: a review.Sensors (Basel, Switzerland) · 2014Review
- Fibrinogen α-chain-derived peptide is upregulated in hippocampus of rats exposed to acute morphine injection and spontaneous alternation testing.Pharmacology research & perspectives · 2014Article
- Localized drug application and sub-second voltammetric dopamine release measurements in a brain slice perfusion device.Analytical chemistry · 2014Article
- Small-volume analysis of cell-cell signaling molecules in the brain.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Review
- Stimulation and release from neurons via a dual capillary collection device interfaced to mass spectrometry.The Analyst · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Neurotransmitters and neuromodulators are molecules within the nervous system that play key roles in cell-to-cell communication. Upon stimulation, neurons release these signaling molecules, which then act at local or distant locations to elicit a physiological response. Ranging from small molecules, such as diatomic gases and amino acids, to larger peptides, these chemical messengers are involved in many functional processes including growth, reproduction, memory and behavior. Understanding signaling molecules and the conditions that govern their release in healthy or damaged networks promises to deliver insights into neural network formation and function. Microfluidic devices can provide optimal cell culture conditions, reduced volume systems, and precise control over the chemical and physical nature of the extracellular environment, making them well-suited for studying neurotransmission and other forms of cell-to-cell signaling. Here we review selected microfluidic approaches that are suitable for monitoring cell-to-cell signaling molecules. We highlight devices that improve in vivo sample collection as well as compartmentalized devices designed to isolate individual neurons or co-cultures in vitro, including a focus on systems used for studying neural injury and regeneration, and devices that allow selective chemical stimulations and the characterization of released molecules.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.