ArticleEnvironmental research2013
Associations of blood and urinary mercury with hypertension in U.S. adults: the NHANES 2003-2006.
Article in Environmental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Re-thinking the link between exposure to mercury and blood pressure.Archives of toxicology · 2025Pooled it
- Mercury Exposure, Blood Pressure, and Hypertension: A Systematic Review and Dose-response Meta-analysis.Environmental health perspectives · 2018Pooled it
- Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999-2012).Scientific reports · 2016Pooled it
- Human Mercury Biomonitoring Under the Minamata Convention: Blood, Urine, Hair, and Tissue Biomarkers (2000-2026).Biological trace element research · 2026Review
- The Association Between Blood Mercury and Lipid Biomarkers in US Hypertensive Adults.Biological trace element research · 2024Article
- Association between heavy metal exposure and biomarkers for non-alcoholic fatty liver disease in Korean adolescents.Heliyon · 2024Article
- Article
- Environmental exposure to lead and cadmium are associated with triglyceride glucose index.Scientific reports · 2024Article
- Contaminant Metals and Cardiovascular Health.Journal of cardiovascular development and disease · 2023Review
- Interaction between blood cadmium and lead concentration and physical activity on hypertension from the Korean national health and nutrition examination survey in 2008-2013.BMC public health · 2023Article
- Associations between mercury exposure with blood pressure and lipid levels: A cross-sectional study of dental professionals.Environmental research · 2023Article
- Family History of Hypertension and Cobalt Exposure Synergistically Promote the Prevalence of Hypertension.Biological trace element research · 2022Article
- The association between blood metals and hypertension in the GuLF study.Environmental research · 2021Article
- Oral methylmercury intoxication aggravates cardiovascular risk factors and accelerates atherosclerosis lesion development in ApoE knockout and C57BL/6 mice.Toxicological research · 2021Article
- Association between Pb, Cd, and Hg Exposure and Liver Injury among Korean Adults.International journal of environmental research and public health · 2021Article
- Low-level exposure to lead, mercury, arsenic, and cadmium, and blood pressure among 8-17-year-old participants of the 2009-2016 National Health and Nutrition Examination Survey.Environmental research · 2021Article
- Does Information on Blood Heavy Metals Improve Cardiovascular Mortality Prediction?Journal of the American Heart Association · 2019Article
- Changes of Atmospheric and Blood Concentrations of Lead and Cadmium in the General Population of South Korea from 2008 to 2017.International journal of environmental research and public health · 2019Article
- Methyl mercury, but not inorganic mercury, associated with higher blood pressure during pregnancy.Environmental research · 2017Article
- Blood mercury concentrations are associated with decline in liver function in an elderly population: a panel study.Environmental health : a global access science source · 2017Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundFew studies have examined the association between hypertension and mercury exposure in the general population. We examined cross-sectional associations between blood (mainly methylmercury) or urinary mercury (mainly inorganic mercury) and hypertension in representative U.S. adults and effect modifications by dietary omega-3 fatty acids and serum selenium.
methodsWe examined 6607 adults aged 20 years or older, using the National Health and Nutrition Examination Survey (NHANES) from 2003/2004 to 2005/2006 (2201 adults were available for urinary mercury from NHANES 2003-2006; 2117 available for serum selenium from NHANES 2003-2004 aged 40 years or older). The average of omega-3 fatty acids from two 24-h recalls was calculated.
resultsThe weighted prevalence of hypertension was 32.2%. The geometric means (95% confidence intervals) of blood total and urinary mercury were 1.03 (0.95, 1.11)μg/L and 0.51 (0.47, 0.54)μg/L, respectively. The adjusted odds ratios for a doubling increase in blood mercury and urinary mercury were 0.94 (0.87 to 1.01) and 0.87 (0.78 to 0.99), respectively, after adjusting for potential confounders. The associations remained similar, even after adjusting for either omega-3 fatty acids or selenium or both. No significant effect modification by either omega-3 fatty acids or selenium was observed.
conclusionsIn this cross-sectional study of the U.S. general population, we found no association of hypertension with blood mercury but a suggestive inverse association with urinary mercury. Future prospective studies are warranted to confirm these findings.
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