ArticleBrain injury2013
Diffusion tensor imaging detects white matter abnormalities and associated cognitive deficits in chronic adolescent TBI.
Article in Brain injury, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Relationship Between Diffusion Tensor Imaging (DTI) Findings and Cognition Following Pediatric TBI: A Meta-Analytic Review.Developmental neuropsychology · 2016Pooled it
- Diffusion Tensor Imaging (DTI) findings following pediatric non-penetrating TBI: a meta-analysis.Developmental neuropsychology · 2014Pooled it
- Imaging the therapeutic effects of cerebral endothelial cell derived exosome treatment of a preclinical model of Alzheimer's disease.Frontiers in aging neuroscience · 2026Article
- Neglect and Neurodevelopment: A Narrative Review Understanding the Link Between Child Neglect and Executive Function Deficits.Biomedicines · 2025Review
- Neuroimaging Correlates of Traumatic Brain Injury in an Older Community-Dwelling Population: The Atherosclerosis Risk in Communities Study.Neurology · 2025Article
- Rapid Prediction and Accurate Location Selection of Mild Traumatic Brain Injury (mTBI) by Using Multiple Parameter Analysis of Diffusion Tensor Imaging (DTI): Integrating Correlational and Clinical Approaches.BioMed research international · 2023Article
- Topological Aberrance of Structural Brain Network Provides Quantitative Substrates of Post-Traumatic Brain Injury Attention Deficits in Children.Brain connectivity · 2021Article
- Diffusion MRI Microstructural Abnormalities at Term-Equivalent Age Are Associated with Neurodevelopmental Outcomes at 3 Years of Age in Very Preterm Infants.AJNR. American journal of neuroradiology · 2021Article
- Frontostriatal White Matter Integrity Relations with "Cool" and "Hot" Self-Regulation after Pediatric Traumatic Brain Injury.Journal of neurotrauma · 2021Article
- Trajectory of Long-Term Outcome in Severe Pediatric Diffuse Axonal Injury: An Exploratory Study.Frontiers in neurology · 2021Article
- Evolving White Matter Injury following Pediatric Traumatic Brain Injury.Journal of neurotrauma · 2021Article
- Neuroimaging of the Injured Pediatric Brain: Methods and New Lessons.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2018Review
- Common Patterns of Regional Brain Injury Detectable by Diffusion Tensor Imaging in Otherwise Normal-Appearing White Matter in Patients with Early Moderate to Severe Traumatic Brain Injury.Journal of neurotrauma · 2018Article
- Relevance of neuroimaging for neurocognitive and behavioral outcome after pediatric traumatic brain injury.Brain imaging and behavior · 2018Article
- Diffusion MRI in pediatric brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
- Reduced white matter integrity in amateur boxers.Neuroradiology · 2016Article
- Structural brain lesions in inflammatory bowel disease.World journal of gastrointestinal pathophysiology · 2015Review
- The Pathophysiology of Sports Concussion.Current pain and headache reports · 2015Review
- Traumatic brain injury imaging research roadmap.AJNR. American journal of neuroradiology · 2015Review
- White matter and reading deficits after pediatric traumatic brain injury: A diffusion tensor imaging study.NeuroImage. Clinical · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
PRIMARY
objectiveThis study examined long-term alterations in white matter microstructure following TBI in adolescence using diffusion tensor imaging (DTI). It was hypothesized that white matter integrity would be compromised in adolescents with TBI and would correlate with measures of executive functioning and cognitive abilities. RESEARCH
designThis study employed whole-brain, voxel-wise, statistical comparison of DTI indices in youth of 12-17 years old (mean = 15.06) with TBI vs an age- and gender-matched cohort (mean age = 15.37). METHODS AND PROCEDURES: This study scanned 17 adolescents with complicated-mild-to-severe TBI, 1-3 years after injury, and 13 healthy adolescents. Tract-Based Spatial Statistics (TBSS) was employed for DTI analysis. MAIN OUTCOMES AND
resultsOverall diffusivity elevations were found in the TBI group with increases in axial diffusivity in the right hemisphere. White matter integrity was associated with word reading, planning and processing times in the TBI group, but not healthy controls.
conclusionsThe detected abnormalities in axial diffusivity may reflect neuronal regeneration and cerebral reorganization after injury. These findings provide tentative evidence of persistent white matter alteration following TBI in adolescence. Associations of DTI indices with cognitive performance following TBI provide tentative support for links between white matter integrity and performance post-TBI.
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