Evidence map›Paper›PMID 23471996›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2013

Next generation antidepressants.

Scott J Russo, Dennis S Charney

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Acetyl-l-carnitine deficiency in patients with major depressive disorder.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Trial
  2. Article
  3. Review
  4. Carnitine and Depression.Frontiers in nutrition · 2022
    Review
  5. Epigenetic Neuropharmacology: Drugs Affecting the Epigenome in the Brain.Annual review of pharmacology and toxicology · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Disruption of lipid-raft localized GαNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  11. Review
  12. Article
  13. Reply to Arduini et al.: Acetyl-l-carnitine and the brain: Epigenetics, energetics, and stress.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  14. Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  15. Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Review
  16. Article
  17. Review
  18. Article
  19. Antidepressant-like properties of novel HDAC6-selective inhibitors with improved brain bioavailability.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Scott J RussoFishberg Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Dennis S Charney

Funding

REPRESSIVE HISTONE AND DNA METHYLATION IN RODENT DEPRESSION MODELSP50MH096890 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALLIS, CHARLES DAVID · 2012 to 2021
$20.2M
Role of thalamic versus cortical inputs to nucleus accumbens in stress-related disordersR01MH090264 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2011 to 2020
$4.2M
NIMH NIH HHS P50 MH096890NIMH NIH HHS R01 MH090264
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcarnitineAnimalsAntidepressive AgentsEpigenesis, GeneticHippocampusHumansMaleNerve Tissue ProteinsPrefrontal CortexReceptors, Metabotropic GlutamateAcetylcarnitineAntidepressive Agentsmetabotropic glutamate receptor 2Nerve Tissue ProteinsReceptors, Metabotropic Glutamate

Identifiers

PMID23471996
PMCPMC3607053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.