ReviewMolecular neurobiology2013
Re-cycling paradigms: cell cycle regulation in adult hippocampal neurogenesis and implications for depression.
Review in Molecular neurobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Intrinsic Excitability of Rat Hippocampal Granule Cells Increases Along the Dorsal-to-Ventral Axis.Hippocampus · 2026Article
- Analysis of Genomic and Transcriptomic Data Revealed Key Genes and Processes in the Development of Major Depressive Disorder.International journal of molecular sciences · 2025Article
- StressMatic: A Novel Automated System to Induce Depressive- and Anxiety-like Phenotype in Rats.Cells · 2023Article
- Melatonin as a Harmonizing Factor of Circadian Rhythms, Neuronal Cell Cycle and Neurogenesis: Additional Arguments for Its Therapeutic Use in Alzheimer's Disease.Current neuropharmacology · 2023Review
- Abnormal Development of Neural Stem Cell Niche in the Dentate Gyrus of Menkes Disease.International journal of stem cells · 2022Article
- Article
- Hippocampal BMP signaling as a common pathway for antidepressant action.Cellular and molecular life sciences : CMLS · 2021Article
- Cell Cycle Regulation of Hippocampal Progenitor Cells in Experimental Models of Depression and after Treatment with Fluoxetine.International journal of molecular sciences · 2021Article
- Review
- Cyclins, Cyclin-Dependent Kinases, and Cyclin-Dependent Kinase Inhibitors in the Mouse Nervous System.Molecular neurobiology · 2020Review
- Pharmacological Stimulation of Nurr1 Promotes Cell Cycle Progression in Adult Hippocampal Neural Stem Cells.International journal of molecular sciences · 2019Article
- Cell-Biological Requirements for the Generation of Dentate Gyrus Granule Neurons.Frontiers in cellular neuroscience · 2018Review
- Establishment of a novel three-dimensional primary culture model for hippocampal neurogenesis.Physiological reports · 2017Article
- Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells.Human molecular genetics · 2017Article
- Injection of Anti-proBDNF in Anterior Cingulate Cortex (ACC) Reverses Chronic Stress-Induced Adverse Mood Behaviors in Mice.Neurotoxicity research · 2017Article
- Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response.Frontiers in molecular neuroscience · 2017Article
- Quantitative assessment of fibroblast growth factor receptor 1 expression in neurons and glia.PeerJ · 2017Article
- Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation.Cell stem cell · 2016Article
- Detection and Phenotypic Characterization of Adult Neurogenesis.Cold Spring Harbor perspectives in biology · 2016Review
- Control of the Cell Cycle in Adult Neurogenesis and its Relation with Physical Exercise.Brain plasticity (Amsterdam, Netherlands) · 2015Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since adult neurogenesis became a widely accepted phenomenon, much effort has been put in trying to understand the mechanisms involved in its regulation. In addition, the pathophysiology of several neuropsychiatric disorders, such as depression, has been associated with imbalances in adult hippocampal neurogenesis. These imbalances may ultimately reflect alterations at the cell cycle level, as a common mechanism through which intrinsic and extrinsic stimuli interact with the neurogenic niche properties. Thus, the comprehension of these regulatory mechanisms has become of major importance to disclose novel therapeutic targets. In this review, we first present a comprehensive view on the cell cycle components and mechanisms that were identified in the context of the homeostatic adult hippocampal neurogenic niche. Then, we focus on recent work regarding the cell cycle changes and signaling pathways that are responsible for the neurogenesis imbalances observed in neuropathological conditions, with a particular emphasis on depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.