ArticleClinical oral investigations2014
Biomimetic treatment on dental implants for short-term bone regeneration.
Article in Clinical oral investigations, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- A Radiographic and Clinical Comparison of Immediate vs. Early Loading (4 Weeks) of Implants with a New Thermo-Chemically Treated Surface: A Randomized Clinical Trial.International journal of environmental research and public health · 2021Trial
- Next-Generation Biomaterials for Hard Tissue Regeneration: Balancing Biofunctionality, Biomimetic Mechanics, and Antimicrobial Resistance.Materials (Basel, Switzerland) · 2026Article
- Controlling Sodium Titanate Crystal Size to Improve Wettability and Early Osseointegration of Titanium Implants: Insights from an Animal Model.Journal of functional biomaterials · 2025Article
- Influence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study.Biomimetics (Basel, Switzerland) · 2025Article
- Effect of the Size of Titanium Particles Released from Dental Implants on Immunological Response.International journal of molecular sciences · 2022Article
- Mineralization of Titanium Surfaces: Biomimetic Implants.Materials (Basel, Switzerland) · 2021Review
- Involvement of FAK/P38 Signaling Pathways in Mediating the Enhanced Osteogenesis Induced by Nano-Graphene Oxide Modification on Titanium Implant Surface.International journal of nanomedicine · 2020Article
- Biofunctionalization with a TGFβ-1 Inhibitor Peptide in the Osseointegration of Synthetic Bone Grafts: An In Vivo Study in Beagle Dogs.Materials (Basel, Switzerland) · 2019Article
- Influence of a Novel Surface of Bioactive Implants on Osseointegration: A Comparative and Histomorfometric Correlation and Implant Stability Study in Minipigs.International journal of molecular sciences · 2019Article
- Influence of the Elastic Modulus on the Osseointegration of Dental Implants.Materials (Basel, Switzerland) · 2019Article
- Effectiveness of a new dental implant bioactive surface: histological and histomorphometric comparative study in minipigs.Clinical oral investigations · 2018Article
- Surface Modification of Ti-35Nb-10Ta-1.5Fe by the Double Acid-Etching Process.Materials (Basel, Switzerland) · 2018Article
- Behavior of Human Osteoblast Cells Cultured on Titanium Discs in Relation to Surface Roughness and Presence of Melatonin.International journal of molecular sciences · 2017Article
- Proteomic analysis of bone proteins adsorbed onto the surface of titanium dioxide.Biochemistry and biophysics reports · 2016Article
- Self-assembled monolayers of alendronate on Ti6Al4V alloy surfaces enhance osteogenesis in mesenchymal stem cells.Scientific reports · 2016Article
- Advances in surfaces and osseointegration in implantology. Biomimetic surfaces.Medicina oral, patologia oral y cirugia bucal · 2015Review
- Current trends in dental implants.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe main purpose of this work was to assess the short-term bone regenerative potential of new osteoconductive implants. The novelty of the study lies in the analysis of the effectiveness of a novel two-step treatment which combines shot-blasting with a thermo-chemical treatment, at very short times after implant placement in a minipig model. MATERIALS AND
methodsThree hundred twenty implants with four different surface treatments, namely bioactivated surfaces, micro-rough grit-blasted, micro-rough acid-etched and smooth as-machined titanium implants were placed into the bone of 20 minipigs. The percent of bone-to-implant contact was determined 3 days, 1, 2, 3 and 10 weeks after implant placement by histomorphometric analysis. Surface composition, topography and wettability of the implant specimens were analysed.
resultsThe combination of shot-blasting and thermo-chemical treatment accelerated bone regeneration at early stages in comparison with all other treatments between day 3 and week 3 (p < 0.05). The value of osseointegration attained at week 2 was maintained until the end of the experiment without any significant changes (percent direct contact ≈ 85 %). This was mostly attributed to the ability of these implants to form in vivo a layer of apatitic mineral that coated the implant and could rapidly stimulate bone nucleation and growth from the implant surface.
conclusionsThe surface quality resulting from this treatment on cpTi provided dental implants with a unique ability of rapid bone regeneration and osseointegration. CLINICAL RELEVANCE: This treatment represents a step forward in the direction of reducing the time prior to implant loading.
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Registered trials
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